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Table 1 ABTC guidelines for target definition

From: Patterns of failure for glioblastoma multiforme following limited-margin radiation and concurrent temozolomide

Target volume Definition
GTV1 T1 enhancing and non-enhancing tumor volume (T2 or FLAIR)
GTV2 T1 enhancing tumor volume
CTV1;2 GTV plus a margin of 5 mm
PTV1;2 CTV plus a margin of 3–5 mm
  1. Note: GTV volume is based on postoperative day 0–1 MRI. GTV, Gross Tumor Volume; CTV, Clinical Target Volume; PTV, planning target volume; ABTC, Adult Brain Tumors Consortium.