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Table 3 Prognostic factors affecting survival on univariate analysis

From: The efficacy of stereotactic body radiation therapy on huge hepatocellular carcinoma unsuitable for other local modalities

Factor

1-yr. survival rate (%)

Hazard ratio (95% confidence interval)

p

Age

   

 ≧60 y.o.

41.2

1.293(0.343-4.882)

0.7

 < 60 y.o.

60

  

Gender

   

 Male

44.4

0.427(0.054-3.344)

0.42

 Female

55.6

  

ECOG

   

 0

66.7

  

 1

47.1

1.656(0.209-13.085)

0.63

 2

50

2.155(0.134-34.555)

0.59

BCLC

   

 B

50

  

 C

50

0.915(0.117-7.176)

0.93

Vascular extension (PVTT & IVCTT)

   

 Yes

37.5

4.920(0.628-38.559)

0.13

 No

83.3

  

Child-Pugh score

   

 A

55

  

 B

0

17.303(2.301-130.129)

0.01

Hepatitis virus

   

 B

50

  

 C

25

1.938(0.483-7.774)

0.35

Non B non C

66.67

0.517(0.104-2.569)

0.42

AFP (IU/mL)

   

 <1500

60

  

 ≧1500

28.6

2.920(0.869-9.809)

0.08

Tumor location

   

 Right

52.38

  

 Left

0

7.629(0.783-74.297)

0.08

Tumor type

   

 Solitary

54.6

  

 Multiple

50

1.447(0.387-5.410)

0.58

 Diffuse

33.3

2.895(0.554-15.129)

0.21

Tumor size

   

 10 cm

57.4

  

 >10 cm

46.67

1.252(0.331-4.729)

0.74

Radiation dose

   

 40 Gy

68.75

  

 < 40 Gy

0

7.922(2.180-28.780)

0.01

Pre-SBRT treatment

   

 Yes

66.7

  

 No

38.5

2.576(0.679-9.777)

0.16

Post-SBRT treatment

   

 Yes

66.7

  

 N0

43.8

2.056(0.443-9.542)

0.36