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Table 2 Summary of dose volume histogram analysis for GTV, brain stem, optic chiasm and ipsi-lateral optic nerve for CSM patients

From: Critical appraisal of RapidArc radiosurgery with flattening filter free photon beams for benign brain lesions in comparison to GammaKnife: a treatment planning study

 

GK_1

GK_2

TB_1

TB_2

p

 

PTV vol [cm3]: 7.28 ± 4.2 Range: [3.3; 13.7]

Mean [Gy]

17.4 ± 0.9

17.4 ± 0.9

13.6 ± 0.2

14.2 ± 0.5

a, b, c, d

D2% [Gy]

22.9 ± 1.4

23.2 ± 1.3

14.4 ± 0.4

15.8 ± 0.8

a, b, c, d

D98% [Gy]

12.25 ± 0.0

12.25 ± 0.0

12.25 ± 0.0

12.25 ± 0.0

-

St. dev [Gy]

2.8 ± 0.2

2.8 ± 0.2

0.5 ± 0.1

0.9 ± 0.3

a, b, c, d

Homogeneity [%]

52.3 ± 2.4

52.7 ± 1.8

12.4 ± 0.6

21.1 ± 0.5

a, b, c, d

PCI

0.86 ± 0.05

0.81 ± 0.06

0.86 ± 0.06

0.88 ± 0.05

c, d

PGI

2.7 ± 0.1

2.6 ± 0.1

3.9 ± 0.7

3.8 ± 0.5

a, b, c, d

DGM [cm]

0.5 ± 0.1

0.5 ± 0.1

0.7 ± 0.1

0.6 ± 0.1

a, b, c, d

 

Brain stem vol [cm 3 ] = 19.9 ± 4.3 Range: [15.36; 26.1]

D1cm3 [Gy]

5.4 ± 2.8

5.5 ± 2.6

5.8 ± 2.0

5.2 ± 2.8

n.s.

V8Gy [%]

2.3 ± 2.7

2.3 ± 2.6

1.8 ± 1.7

1.8 ± 1.6

n.s.

V10Gy [%]

0.7 ± 0.8

0.7 ± 0.7

0.5 ± 0.6

0.4 ± 0.4

n.s.

V12Gy [%]

0.1 ± 0.1

0.1 ± 0.1

0.1 ± 0.1

0.0 ± 0.1

n.s.

 

Optic chiasm vol [cm 3 ] = 0.5 ± 0.3 Range: [0.3; 0.9]

D0.1cm3 [Gy]

6.8 ± 3.4

5.9 ± 3.1

5.1 ± 2.9

4.5 ± 2.1

a, b, d

 

Ipsilateral optic nerve vol [cm 3 ] = 0.5 ± 0.1 Range: [0.4;0.5]

D0.1cm3 [Gy]

4.2 ± 2.1

4.2 ± 2.1

2.9 ± 1.6

2.1 ± 1.5

a, b, c, d

  1. Statistical significance p: a = GK_1 vs TB_1, b = GK_1 vs TB_2, c = GK_2 vs TB_1, d = GK_2 vs TB_2; n.s. = not significant. PCI = Paddick Conformity Index, PGI = Paddick Gradient Index, DGM = Dose Gradient measure. Dx% = Dose at x% of the volume.