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Table 3 Median radiation doses to cavernous sinus, optic nerves and chiasm in patients treated with multi-fraction SRS (5 × 5 Gy)

From: Fractionated stereotactic radiosurgery for patients with skull base metastases from systemic cancer involving the anterior visual pathway

Site

Median

Maximum

Organ at risk

Volume (cm3)

Volume (cm3)

 

dose

dose

volume

receiving

receiving

 

(Gy)

(Gy)

(cm3)

a dose > 25.0 Gy

a dose > 27.5 Gy

Cavernous sinus

18.5

29

1.9 (1.44-2.52)

1.7 (1.41-2.4)

0.52 (0.2-1.9)

Optic nerve

13.5

28.5

0.93 (0.71-1.26)

0.08 (0.01-0.5)

0.026 (0.005-0.08)

Optic chiasm

5.5 (12*)

28.5

0.48 (0.33-0.71)

0.13 (0.03-0.28)*

0.022 (0.01-0.06)*

  1. *In 18 patients receiving a total dose to the optic chiasm >25 Gy.