Table 2 Univariate and multivariate analysis of prognostic factors for overall survival and distant failure
Variable | Median | Univariate | Multivariate analysis | |
|---|---|---|---|---|
Survival time (months) | Analysis P value | Hazard ratio (95% CI) | P value | |
Overall survival | ||||
Sex, male vs female | male (16.1); female (13.5) | 0.1 | ||
Age (years), < 65 vs ≥ 65 | < 65 (15.0); ≥ 65 (11.5) | 0.1 | ||
KPS, ≤ 70 vs >70 | ≤ 70 (11.5); >70 (20.3) | 0.001 | 0.30 (0.1-0.68) | 0.01 |
Primary tumor, breast cancer vs others | breast cancer (13.0); others (15.5) | 0.2 | ||
Extracranial metastases, absent vs present | absent (22.5); present (11.2) | 0.0001 | 0.10 (0.05-0.40) | 0.001 |
Number of metastases, 1 vs > 1 | 1 met (15.5); >1 met (13.2) | 0.3 | ||
Distant brain failure | ||||
Sex, male vs female | male (16.1); female (13.5) | 0.9 | ||
Age (years), < 65 vs ≥ 65 | < 65 (12.0); ≥ 65 (10.0) | 0.2 | ||
KPS, ≤ 70 vs >70 | ≤ 70 (8.0); >70 (16.0) | 0.03 | 0.36 (0.16-1.27) | 0.1 |
Primary tumor, breast cancer vs others | breast cancer (10.0); others (14.0) | 0.1 | ||
Extracranial metastases, absent vs present | absent (18.0); present (8.0) | 0.002 | 0.18 (0.07-0.64) | 0.01 |
Number of metastases, 1 vs > 1 | 1 met (16.0); > 1 met (10.0) | 0.1 | ||