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Table 1 Summary of different ITVs and investigated parameters for volumetric and dosimetric changes

From: Reconstitution of internal target volumes by combining four-dimensional computed tomography and a modified slow computed tomography scan in stereotactic body radiotherapy planning for lung cancer

ITV

Definition

ITVall

Volume generated by combining the GTVs from all 8 phases of 4D CT

ITV2

Volume generated by combining the GTVs from 2 extreme phases of 4D CT

ITVslow

Volume derived from the GTV on a modified slow CT scan

ITVall+slow

Volume generated by combining ITVall and ITVslow

ITV2+slow

Volume generated by combining ITV2 and ITVslow

Change

Parameter

Volume

Absolute volume, PVD

Shape/Location

POV, Geometric coverage (Missing volume) for a specific ITV

Lung-dose

MLD, V5, V10, V20, V25, V30

  1. Abbreviations: ITV internal target volume; GTV gross tumor volume; 4D CT four-dimensional computed tomography; PVD percentage volume difference; POV percentage of overlap volume, defined as the ratio between the overlapping and encompassing volume; MLD mean lung dose; V5, V10, V20, V25, and V30, percentage volumes of both lungs minus the PTV receiving more than 5, 10, 20, 25, and 30 Gy.