Table 1 Baseline patient characteristics, N = 340, WBRT – whole brain radiotherapy
Characteristic | Patients |
|---|---|
Median follow-up | 721 days |
Sex | |
• Male | 159 (46.8%) |
• Female | 181 (53.2%) |
Median age | 62 |
Age | |
• < 65 y | 208 (61.2%) |
• ≥ 65 y | 132 (38.8%) |
WBRT | |
• No | 189 (55.6%) |
• Yes | 151 (44.4%) |
RPA class | |
• I | 26 (7.7%) |
• II | 271 (79.7%) |
• III | 43 (12.6%) |
Karnofsky Performance Score | |
• ≤ 70 | 82 (24.1%) |
• > 70 | 258 (75.9%) |
Number of cerebral metastases | |
• 1 | 197 (57.9%) |
• 2 | 101 (29.7%) |
• 3 | 31 (9.1%) |
• 4 | 8 (2.4%) |
• 5 | 2 (0.6%) |
• 7 | 1 (0.3%) |
Histology | |
• NSCLC | 160 (47.1%) |
• SCLC | 27 (7.9%) |
• Malignant Melanoma | 49 (14.4%) |
• Breast Cancer | 41 (12.1%) |
• Renal Cell Carcinoma | 20 (5.9%) |
• Others | 43 (12.6%) |
Median radiation volume | 1.7 ml |
Median dose to the 80% isodose | 20 Gy |
Radiation necrosis | |
• Yes | 21 (6.2%) |
• No | 319 (93.8%) |