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Table 3 Clinical and dosemiteric factors in patients with and without hypothyroidism

From: V30 as a predictor for radiation-induced hypothyroidism: a dosimetric analysis in patients who received radiotherapy to the neck

 

Normal

Hypothyroidism

P

 

(n = 48)

(n = 52)

 

Median Age (year)

53

48

0.23

Comorbidity

9

8

0.30

Surgery

16

14

0.26

Chemotherapy

32

29

0.22

Gender

  

0.12

  Female

46%

54%

 

  Male

60%

40%

 
 

Median (range)

 

Thyroid volume

31.59 (5.7–99)

14.25 (0.6–69.6)

0.01

Dmin (≥40.1 Gy)

48.1 (0–61.0)

52.1 (0.6–59.7)

0.42

Dmax (≥57.6 Gy)

50 (19.9–75.3)

47.9 (19.4–71.0)

0.49

Dmean (≥47.3 Gy)

44.2 (5.7–67.3)

56.2 (3.8–66.5)

0.03

V10 (≥100%)

75.0 (13–100)

89.1 (9–100)

0.06

V20 (≥100%)

67.5 (7–100)

82.6 (0–100)

0.06

V30 (≥100%)

59.6 (0–100)

78.3 (0–100)

0.03

V40 (≥94%)

45.9 (0–100)

53.6 (0–100)

0.36

V50 (≥44%)

54.8 (0–100)

45.2 (0–100)

0.06