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Table 2 SBRT characteristics

From: Toxicity and outcomes of thoracic re-irradiation using stereotactic body radiation therapy (SBRT)

SBRT Characteristics

Total

Overlap with prior RT

No overlap

 

N = 39

N = 22

N = 17

Median BED10 , Gy (range)

70 (43–180)

48 (43–106)

106 (58–180)

BED10 ≥ 100 Gy, N (%)

15 (38)

4 (18)

11 (65)

  60 Gy in 3 fr (BED10 = 180 Gy)

3

  

  54 Gy in 3 fr ( BED10 = 151 Gy)

4

  

  48 Gy in 4 fr ( BED10 = 106 Gy)

8

  

BED10 < 100 Gy, N (%)

24 (62)

18 (82)

6 (35)

  40-45 Gy in 5 fr ( BED10 = 72-86 Gy)

4

  

  20-22 Gy in 1 fr ( BED10 = 60-70 Gy)

4

  

  32-35 Gy in 4–5 fr ( BED10 = 54-59 Gy)

4

  

  27.5-30 Gy in 5 fr ( BED10 = 43-48 Gy)

12

  

Median PTV size, cm3 (range)

67 (17–473)

117 (20–473)

45 (17–197)

Median GTV size, cm3 (range)

19 (0.7-227)

43 (2–227)

6 (0.7-74)

Median ipsilateral lung mean dose, Gy (range)

6.3 (1.7-13.1)

4.8 (1.7-13.1)

6.6 (1.7-13.1)

Median combined lung mean dose, Gy (range)

3.2 (0.8-7.2)

3.1 (1.1-6.2)

4.3 (0.8-7.2)

Median ipsilateral lung V20, % (range)

10 (2–30)

10 (2–30)

12 (3–25)

Median combined lung V20, % (range)

5 (1–12)

5 (1–10)

5 (2–12)

  1. BED 10 , Biologically equivalent dose for α/β = 10; PTV, Planning treatment volume; GTV, Gross tumor volume; V20, Percent of volume receiving 20 Gy or more.