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Table 1 Dose volume parameters

From: Re-irradiation of recurrent head and neck carcinomas: comparison of robust intensity modulated proton therapy treatment plans with helical tomotherapy

 

Patient 1

Patient 2

Patient 3

Patient 4

Patient 5

Patient 6

Patient 7

 

Proton / Photon

Proton / Photon

Proton / Photon

Proton / Photon

Proton / Photon

Proton / Photon

Proton / Photon

CTV

60

33

97

71

127

197

115

 

11

66

Paddick CI95

0.83 / 0.93

0.46 / 0.58

0.57 / 0.66

0.46 / 0.71

0.69 / 0.79

0.78 / 0.74

0.69 / 0.71

0.21 / 0.46

0.58 / 0.64

D98

86.5 / 91.2

100.6 / 102.0

100.9 / 99.4

86.2 / 85.7

99.9 / 99.9

79.0 / 82.1

100.4 / 101.8

101.3 / 100.5

104.7 / 101.3

D95

97.5 / 98.5

102.0 / 102.3

101.1 / 99.7

88.4 / 85.5

101.2 / 100.5

80.9 / 82.8

100.4 / 102.1

    

101.4 / 100.8

 

101.2 / 103.2

 

D50

104.4 / 105.3

105.3 / 103.8

103.8 / 101.3

95.6 / 89.9

105.2 / 102.6

91.6 / 88.2

104.0 / 103.3

    

104.2 / 102.0

 

104.7 / 104.7

 

D2-D98

30.3 / 16.5

13.5 / 4.1

9.2 / 4.2

26.6 / 15.9

12.2 / 5.0

24.5 / 20.8

9.9 /3.4

    

16.2 / 3.2

 

8.4 / 3.4

 

Spinal Cord

       

D2

8.7 / 4.8

9.2 / 14.4

2.6 / 9.7

4.7 / 5.9

5.3 / 13.2

8.5 / 8.7

13,7 / 19.3

Dmax

16.6 / 8.2

13.5 / 18.7

10.2 / 16.0

14.4 / 13.7

13.3 / 18.7

15.4 / 13.3

25.0 / 28.1

Brain stem

       

D1cc

18.8 /21.6

41.0 / 45.0

11.6 / 11.9

14.3 / 16.5

30.6 / 46.5

3.8 / 5.0

4.7 / 6.2

Dmax

38.5 /40.0

79.5 / 78.7

30.1 / 22.7

33.5 / 25.0

61.6 / 64.5

8.2 / 9.0

13.6 / 10.6

ipsilat. Optic Nerve

       

Dmax

32.5 / 13.8

22.6 / 26.1

11.9 / 3.8

3.9 / 2.4

2.8 / 18.6

0.0 / 1.6

0.0 / 1.2

Chiasma Opticum

       

Dmax

18.7 / 15.4

28.1 / 15.1

0.8 / 3.4

6.3 / 2.7

2.0 / 16.0

0.0 / 1.4

0.0 / 1.2

Temporal Lobes

       

ipsilat. Dmean

17.9 / 21.9

54.4 / 50.9

5.9 / 10.7

28.6 / 15.5

47.3 / 57.1

0.3 / 1.6

0.7 / 1.2

ipsilat. D1cc

72.5 / 77.7

98.3 / 99.8

32.0 / 34.6

86.1 / 76.1

106.8 / 100.8

2.8 / 3.1

0.1 / 2.1

contoured Cerebellum

       

Dmean

9.0 / 18.4

13.3 / 26.2

0.5 / 9.8

9.1 / 16.4

11.1 / 32.1

0.2 / 2.5

0.1 / 1.4

D5cc

53.9 / 53.7

69.7 / 60.7

3.7 / 21.7

52.0 / 47.2

74.1 / 67.9

2.0 / 9.4

1.2 / 2.8

Parotid Glands

       

Dmean

37.3 / 26.9

3.0 / 4.5

17.6 / 33.0

1.2 / 7.9

0.0 / 4.8

24.3 /39.0

48.7 / 47.8

contoured Jaw

       

V80

0.6 / 0.1

4.1 / 2.2

11.2 / 11.5

16.6 / 10.5

7.8 / 6.7

5.7 / 6.0

9.3 / 10.1

Dmean

13.0 / 7.4

8.6 / 8.4

20.9 / 24.4

35.9 / 34.3

12.3 / 15.6

34.2 / 48.0

25.4 / 39.4

scanned Body

       

Dmean

10.2 / 11.1

6.9 / 9.5

7.2 / 9.7

4.4 / 4.4

3.2 / 5.7

3.7 / 5.3

3.6 / 4.9

V95

89 / 83

73 / 57

171 / 147

156 / 100

186 / 161

254 / 266

167 / 162

V90

108 / 92

87 / 64

193 / 167

178 / 112

205 / 177

281 / 291

190 / 180

V80

143 / 112

114 / 77

234 / 200

221 / 132

247 / 207

337 / 343

231 / 212

PTV

81

49

124

92

152

246

147

 

17

92

  1. Dose volume parameters related to target coverage, homogeneity and the exposure of normal tissues by helical tomotherapy (Photon) and intensity modulated proton therapy (Proton). All doses were given in percent of the prescribed dose, all volumes in cm3. Patients 4 and 6 were treated by an integrated boost technique and their plans were normalized to the prescribed boost dose. For these two patients, the respective cells for the D2 to D98 values were split and the values for the boost clinical target volume (CTV) were given in the lower half and for the larger CTV1 in the upper half of the cell.