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Table 3 Postoperative acute toxicities

From: Phase II trial of preoperative radiochemotherapy with concurrent bevacizumab, capecitabine and oxaliplatin in patients with locally advanced rectal cancer

Toxicities

Patients, n (%)

Grade 1

Grade 2

Grade 3

Grade 4

Hematological

    

Leucopenia

2(3)

1(1)

1(1)

-

Non-hematological

    

Palmar-plantar erythrodysesthesia

14(20)

2(3)

1(1)

-

Fatigue

11(16)

2(3)

1(1)

-

Diarrhea

6(9)

2(3)

3(4)

-

Paresthesia

5(7)

5(7)

-

-

Ileus

-

-

-

1(1)

Nausea

2(3)

1(1)

1(1)

-

Proctitis

-

-

1(1)

-

Abdominal pain

-

-

1(1)

-

Anal fistula

-

-

1(1)

-

Pelvic abscess

-

-

1(1)

-

Sensory neuropathy

1(1)

4(6)

1(1)

-

Somnolence

-

-

1(1)

-

Delayed woundhealing

-

-

1(1)

-