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Table 4 Proportion of variance explained in the QoL parameters by each of the demographic and clinical variables for the boost groups (IORT-EBRT, IORTboost, and EBRTboost; results from univariate linear regression analyses)

From: Radiation-related quality of life parameters after targeted intraoperative radiotherapy versus whole breast radiotherapy in patients with breast cancer: results from the randomized phase III trial TARGIT-A

 

Global health status

Restrictions in daily activities

General pain

Breast symptoms

Arm symptoms

Age

3,1%*

2,1%

4,5%*

1%

0,0%

Married/partnered

0,9%

1,6%

1,1%

0,6%

0,3%

Employed

2,4%

3,7%*

4,8%*

0,0%

0,7%

Months since BCS

2,6%*

1,2%

0,3%

1,4%

0,8%

Tumor size

1,3%

0,5%

0,8%

0,2%

0,2%

Nodal involvement

0,6%

0,3%

1,3%

1,3%

0,3%

ALND

1,0%

0,0%

0,0%

0,8%

0,0%

Chemotherapy

3,4%*

3,3%*

4,5%*

0,3%

0,2%

Endocrine therapy

0,0%

0,2%

0,0%

0,7%

0,1%

Radiotherapy of supra- and infraclavicular nodes

1,0%

0,0%

0,2%

0,6%

0,1%

Medical comorbidities ≥2

15,0%**

11,0%**

17,7%**

0,0%

4,9%*

  1. * p < 0,05 in the univariate analysis.
  2. ** p < 0,05 in the univariate and multivariate analyses.