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Table 3 Summary of DVH-based analysis for OARs and healthy tissue

From: Post mastectomy linac IMRT irradiation of chest wall and regional nodes: dosimetry data and acute toxicities

Organ/Structure

Parameters

Plans

Value (Mean±SD)

P-value

Ipsilateral lung

V5

All

65%±8%

 
  

Integrated

67%±9%

0.005

  

Segmented

61%±7%

 
 

V20

All

28%±2%

 
  

Integrated

28%±3%

0.980

  

Segmented

28%±2%

 
 

Dmean (Gy)

All

15.06±1.66

 
  

Integrated

15.11±1.54

0.658

  

Segmented

14.93±1.99

 

Contralateral lung

V5

All

12%±11%

 
  

Integrated

14%±12%

0.157

  

Segmented

9%±8%

 
 

Dmean (Gy)

All

2.26±1.32

 
  

Integrated

2.58±1.43

0.019

  

Segmented

1.66±0.83

 

Heart

V5

Left-sided lesions

56%±15%

 
  

Integrated

60%±13%

0.001

  

Segmented

45%±13%

 
 

V10

Left-sided lesions

30%±9%

 
  

Integrated

31%±10%

0.076

  

Segmented

26%±7%

 
 

V20

Left-sided lesions

13%±6%

 
  

Integrated

14%±7%

0.77

  

Segmented

13%±4%

 
 

V30

Left-sided lesions

7%±3%

 
  

Integrated

8%±4%

0.21

  

Segmented

6%±3%

 
 

Dmean (Gy)

Left-sided lesions

8.69±1.47

 
  

Integrated

8.76±1.61

0.65

  

Segmented

8.54±1.14

 

Spinal cord

Dmax (Gy)

All

36.10±5.87

 
  

Integrated

37.24±4.55

0.009

  

Segmented

33.29±7.97

 

Ipsilateral humeral head

Dmean (Gy)

All

23.98±9.25

 
  

Integrated

28.22±5.60

<0.001

  

Segmented

12.31±6.99

 

Esophagus

Dnear-max (Gy)

All

41.56±7.79

 
  

Integrated

41.84±9.15

0.85

  

Segmented

41.29±6.47

 
 

Dmean (Gy)

All

11.14±3.11

 
  

Integrated

11.22±2.78

0.745

  

Segmented

10.83±4.27

 

Contralateral breast

Dmean (Gy)

All

0.98±0.46

 
  

Integrated

1.01±0.48

0.418

  

Segmented

0.90±0.43

 
 

V5

All

2%±1%

 
  

Integrated

2%±2%

0.299

  

Segmented

1%±1%

 

Healthy tissue

EI

All

0.30±0.04

 
  

Integrated

0.31±0.03

0.094

  

Segmented

0.28±0.05

 
  1. Abbreviations: Vx: percent volume of critical structures receiving a dose of x Gy; EI: external volume index; other abbreviations as in Table 2.