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Table 1 Patient and disease characteristics (n = 555)

From: Patterns of radiotherapy practice for biliary tract cancer in Japan: results of the Japanese radiation oncology study group (JROSG) survey

Characteristic Patients (%)
Age (median, 69 y)  
  < 70 y 288 (51.9)
  ≥ 70 y 267 (48.1)
Gender  
  Female 183 (33.0)
  Male 372 (67.0)
Pathologic type, verified  
  Yes, adenocarcinoma 417 (75.1)
  Yes, other 5 (0.9)
  No 133 (24.0)
Ultrasonography (before RT)  
  Yes 451 (81.3)
  No 21 (3.8)
  Unknown 83 (14.9)
CT (before RT)  
  Yes 515 (92.8)
  No 5 (0.9)
  Unknown 35 (6.3)
MRCP (before RT)  
  Yes 324 (58.4)
  No 152 (27.4)
  Unknown 79 (14.2)
PTCD  
  Yes 242 (43.6)
  No 151 (27.2)
  Unknown 162 (29.2)
Primary site  
  Intrahepatic bile duct 71 (12.8)
  Gallbladder 42 (7.6)
  Extrahepatic bile duct 439 (79.1)
  Perihilar 278 (50.0)
  Distal 144 (25.9)
  Unknown 17 (3.1)
  Ampulla of Vater 3 (0.5)
Maximal tumor size (Median, 4.0 cm)  
  < 4.0 cm 195 (35.1)
  ≥ 4.0 cm 198 (35.7)
  Unknown 162 (29.2)
Tumor emboli  
  Yes 32 (5.8)
  No 292 (52.6)
  Unknown 231 (41.6)
ECOG performance status  
  0 223 (40.2)
  1 226 (40.7)
  2 77 (13.8)
  3 17 (3.1)
  4 1 (0.2)
  Unknown 11 (2.0)
Jaundice  
  Yes 355 (64.0)
  No or unknown 200 (36.0)
CA19-9 (U/mL)  
  < 37 102 (18.4)
  37-1,000 253 (45.6)
  ≥ 1,000 81 (14.6)
  Unknown 119 (21.4)
CEA (ng/ml)  
  < 5 300 (54.1)
  5-10 63 (11.3)
  ≥ 10 49 (8.8)
  Unknown 143 (25.8)
Alcohol consumption  
  Yes 193 (34.8)
  No 223 (40.2)
  Unknown 139 (25.0)
Smoking  
  Yes 175 (31.5)
  No 239 (43.1)
  Unknown 141 (25.4)
Diabetes mellitus  
  Yes 75 (13.5)
  No 383 (69.0)
  Unknown 97 (17.5)
Clinical T stage  
  TX 11 (2.0)
  T1 41 (7.4)
  T2 147 (26.4)
  T3 183 (33.0)
  T4 112 (20.2)
  Unknown 61 (11.0)
Clinical N stage  
  N0 310 (55.9)
  N1 165 (29.7)
  Unknown 80 (14.4)
Clinical stage  
  I 96 (17.3)
  II 202 (36.4)
  III 146 (26.3)
  IV 25 (4.5)
  Unknown 86 (15.5)
Resectable at diagnosis  
  Yes 254 (45.8)
  No 288 (51.9)
  Unknown 13 (2.3)
Investigational protocol  
  Yes 0 (0)
  No 555 (100)
  1. Abbreviations: RT Radiotherapy; CT Computed tomography; MRCP Magnetic retrograde cholangiopancreatography; PTCD Percutaneous transhepatic cholangiodrainage; ECOG Eastern cooperative oncology group; CEA Carcinoembryonic antigen; CA19-9 Carbohydrate antigen 19–9.