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Table 1 Plan comparison parameters* between TB-IMRT and CBR techniques

From: Template-based breast IMRT planning for increased workload efficiency

Structure Parameters TB-IMRT CBR p value
TV CI 0.68 (0.083) 0.59 (0.15) 0.003
HI 0.096 (1.2) 0.13 (2.2) < 0.001
Mean dose (%) 100.4 (0.80) 99.8 (2.6) 0.37
Maximal dose (%) 106.7 (0.85) 106.3 (0.97) 0.12
Ipsilateral lung V5 (%) 22.2 (8.0) 20.3 (8.2) 0.09
V20 (%) 12.5 (5.0) 12.9 (5.2) 0.41
Contralateral lung V0.5 (%) 4.7 (8.1) 10.3 (9.5) 0.006
V5 (%) Negligible Negligible NS
Heart V1 (%) 33.5 (2.2) 39.1 (21) 0.006
V5 (%) 4.91 (6.5) 4.7 (5.1) 0.67
V25 (%) 2.2 (3.8) 2.2 (2.5) 0.32
Contralateral breast V1 (%) 1.4 (2.1) 6.2 (4.4) 0.0003
V5 (%) Negligeable Negligeable NS
  1. Abbreviations: D2% and D98% are the maximum and minimum dose that covers 2% and 98% volume of the PTV on dose volume histogram; TB-IMRT = template-based intensity-modulated radiation therapy; NS = non significant; TV = treated volume; Vn (5) = percent volume receiving n Gy or greater.
  2. *Average values (standard deviation) for the 20 patients.
  3. Two-sided paired t test.