Treatment | LN18 | T98G | U87 | U251 | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | α (Gy-1) | β (Gy-2) | SER50 (p) | SER37 (p) | α (Gy-1) | β (Gy-2) | SER50 (p) | SER37 (p) | α (Gy-1) | β (Gy-2) | SER50 (p) | SER37 (p) | α (Gy-1) | β (Gy-2) | SER50 (p) | SER37 (p) |
X-rays | 0.08 ± 0.02 | 0.04 ± 0.01 | - | - | 0.04 ± 0.02 | 0.05 ± 0.01 | - | - | 0.15 ± 0.04 | 0.04 ± 0.01 | - | - | 0.01 ± 0.02 | 0.06 ± 0.01 | - | - |
X-rays + 5/10 μM TMZ | 0.13 ± 0.02 | 0.04 ± 0.01 | 1.08 (0.32) | 1.06 (0.36) | 0.02 ± 0.01 | 0.05 ± 0.01 | 0.95 (0.52) | 0.96 (0.50) | 0.12 ± 0.05 | 0.05 ± 0.01 | 0.99 (0.93) | 1.01(0.92) | 0.04 ± 0.03 | 0.06 ± 0.01 | 1.08 (0.24) | 1.06 (0.30) |
X-rays + 5 μM ABT-888 | 0.18 ± 0.02 | 0.04 ± 0.01 | 1.28 (0.01) | 1.23 (0.01) | 0.12 ± 0.02 | 0.04 ± 0.01 | 1.16 (0.25) | 1.12 (0.20) | 0.21 ± 0.02 | 0.04 ± 0.01 | 1.13 (0.16) | 1.12 (0.17) | 0.12 ± 0.02 | 0.07 ± 0.01 | 1.37 (0.002) | 1.31 (0.002) |
X-rays + 5 μM ABT-888 + 5/10 μM TMZ | 0.16 ± 0.01 | 0.05 ± 0.01 | 1.25 (0.02) | 1.21 (0.01) | 0.15 ± 0.01 | 0.04 ± 0.01 | 1.30 (0.03) | 1.24 (0.01) | 0.33 ± 0.02 | 0.02 ± 0.01 | 1.30 (0.03) | 1.24 (0.04) | 0.20 ± 0.01 | 0.05 ± 0.01 | 1.44 (0.003) | 1.35 (0.001) |