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Table 2 Dose and response statistics for initial treatment plans (39 fractions)

From: Employing the therapeutic operating characteristic (TOC) graph for individualised dose prescription

  

3D-CRT

IMRTphys

IMRTbiol

prostate

    
 

Dmin

77.1

75.4

74.1

 

Dmean

78.2

78.8

81.8

 

Dmax

79.1

81.8

97.0

 

TCP

83%

83%

87%

rectum

    
 

Dmean

47.7

36.8

36.3

 

Dmax

78.9

80.1

84.7

 

NTCPGI

25%

13%

13%

bladder

    
 

Dmean

33.3

25.1

17.7

 

Dmax

77.9

82.4

93.8

 

NTCPGU

15%

14%

14%

  1. Abbreviations: 3D-CRT, three-dimensional conformal radiation therapy; IMRT phys , physically optimised IMRT plan; IMRT biol , physico-biologically optimised IMRT plan; D min , minimum dose; D mean , mean dose; D max , maximum dose, TCP, tumour control probability, NTCP GI , probability of late gastrointestinal morbidity; NTCP GU , probability of late genitourinary morbidity.