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Table 2 Dose and response statistics for initial treatment plans (39 fractions)

From: Employing the therapeutic operating characteristic (TOC) graph for individualised dose prescription

   3D-CRT IMRTphys IMRTbiol
prostate     
  Dmin 77.1 75.4 74.1
  Dmean 78.2 78.8 81.8
  Dmax 79.1 81.8 97.0
  TCP 83% 83% 87%
rectum     
  Dmean 47.7 36.8 36.3
  Dmax 78.9 80.1 84.7
  NTCPGI 25% 13% 13%
bladder     
  Dmean 33.3 25.1 17.7
  Dmax 77.9 82.4 93.8
  NTCPGU 15% 14% 14%
  1. Abbreviations: 3D-CRT, three-dimensional conformal radiation therapy; IMRT phys , physically optimised IMRT plan; IMRT biol , physico-biologically optimised IMRT plan; D min , minimum dose; D mean , mean dose; D max , maximum dose, TCP, tumour control probability, NTCP GI , probability of late gastrointestinal morbidity; NTCP GU , probability of late genitourinary morbidity.