Figure 2

Histograms showing attenuation and/or complete suppression of 59 IR-induced NFκB signaling pathway genes with CUR, EF24, NLE, GEN, RES or RSE treatment in hypoxic human breast adenocarcinoma cells. QPCR profiling was performed using human NFκB signaling pathway profiler (Realtimeprimers.com, Elkins Park, PA) containing 88 genes and 8 internal controls. The ΔΔ^ct values calculated by normalizing the gene expression levels to the expression of the housekeeping genes were compared between groups and expressed as fold change.