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Table 2 Protocol treatment goals

From: Phase I study of hypofractionated intensity modulated radiation therapy with concurrent and adjuvant temozolomide in patients with glioblastoma multiforme

Volume

Goal 1

Goal 2

Goal 3

PTV

60 Gy to ≥ 95% of the PTV

≤ 20% of the PTV to > 66 Gy

≤ 1% of the PTV to < 54 Gy

Optic Chiasm

≤ 5% to > 47.25 Gy

≤ 33% to 40.5 Gy

 

Optic nerves

≤ 5% to > 47.25 Gy

≤ 33% to 40.5 Gy

 

Brainstem

≤ 5% to > 52.5 Gy

≤ 33% to 45 Gy

 

Spinal cord

≤ 5% to > 42 Gy

≤ 33% to 36 Gy

 

Eyes

≤ 5% to > 10.5 Gy

≤ 33% to 9 Gy

 
  1. Abbreviations: PTV: planning target volume.