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Table 2 Multivariate analysis of overall survival using Cox proportional hazard model

From: Radiation therapy for epithelial ovarian cancer brain metastases: clinical outcomes and predictors of survival

Variable

Event(n)/

Hazard ratio

p Value

 

Total (n)

  

KPS at BM diagnosis

   

≥70 (reference)

37/42

1.00

 

<70

9/9

2.86

0.018

Primary tumor controlled in abdomen

   

Yes (reference)

31/36

1.00

 

No

23/23

2.84

0.008

Number of BM or LMD

   

1 (reference)

24/28

1.00

 

2-3

8/10

1.51

0.490

4+

16/16

3.18

0.053

LMD

6/6

8.22

0.013

  1. Event = death. BM = brain metastasis; KPS = Karnofsky Performance Score; LMD = leptomeningeal disease.