Table 1 Clinical characteristics at time of initial brain metastases

Median age at BM Dx

56.1 years

31.2-79.0

Median interval from EOC Dx to BM

3.4 years

0.08-26.8

Median interval from EOC Dx to BM in stage I-II EOC

5.9 years

3.7-10.8

Median interval from EOC Dx to BM in stage III-IV EOC

3.1 years

0.08-26.8

Number

Percent

Age <65

52

87%

Age ≥65

8

13%

KPS <70

9

15%

KPS ≥70

42

70%

KPS unknown

9

15%

Number of BM at initial BM Dx:

1

28

46.7%

2-3

10

16.7%

≥4

16

26.7%

LMD

6

10%

Location of initial BM:

Cerebral hemispheres

29

48%

Cerebellum

10

17%

Both

21

35%

Extracranial metastases at time of BM Dx:

None

10

17%

Limited and stable

11

18%

Limited and progressive

11

18%

Extensive and stable

11

18%

Extensive and progressive

16

27%

Unknown

1

2%

Primary tumor status (abdomen):

Controlled

36

60%

Uncontrolled

23

38%

Unknown

1

2%

Chemotherapy in 3 months preceding BM Dx:

Yes

37

62%

No

23

38%