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Table 3 Dosimetric comparison within the same cohort: IMRT-SIB technique versus classic 3DCRT technique

From: Adjuvant concurrent chemoradiation using intensity-modulated radiotherapy and simultaneous integrated boost for resected high-risk adenocarcinoma of the distal esophagus and gastro-esophageal junction

Metric

IMRT-SIB

3DCRT

p (2-sided t-test)

V20 (TL-CTV1) (−)

0.30

0.40

< 0.005

V10 (TL-CTV1) (−)

0.68

0.54

< 0.005

mean dose (TL-CTV1) (cGy)

1616.9

1760.4

0.070

liver mean dose (cGy)

1748.3

1919.2

0.10

heart mean dose (cGy)

2981.2

3582.9

< 0.005

cord maximum (absolute) (cGy)

4175.0

4587.3

< 0.005

cord maximum (2 cm3 volume) (cGy)

3935.9

4422.5

< 0.005

right kidney mean dose (cGy)

474.2

641.8

0.29

left kidney mean dose (cGy)

645.4

966.0

0.26

mean value of (D95*/prescription dose) for PTV1 (−)

0.97

0.98

0.70

mean value of (D95*/prescription dose) for PTV2 (−)

0.97

0.98

0.48

  1. *D95: dose delivered to ≥ 95% of reference volume PTV1 or PTV2.