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Table 3 Dosimetric comparison within the same cohort: IMRT-SIB technique versus classic 3DCRT technique

From: Adjuvant concurrent chemoradiation using intensity-modulated radiotherapy and simultaneous integrated boost for resected high-risk adenocarcinoma of the distal esophagus and gastro-esophageal junction

Metric IMRT-SIB 3DCRT p (2-sided t-test)
V20 (TL-CTV1) (−) 0.30 0.40 < 0.005
V10 (TL-CTV1) (−) 0.68 0.54 < 0.005
mean dose (TL-CTV1) (cGy) 1616.9 1760.4 0.070
liver mean dose (cGy) 1748.3 1919.2 0.10
heart mean dose (cGy) 2981.2 3582.9 < 0.005
cord maximum (absolute) (cGy) 4175.0 4587.3 < 0.005
cord maximum (2 cm3 volume) (cGy) 3935.9 4422.5 < 0.005
right kidney mean dose (cGy) 474.2 641.8 0.29
left kidney mean dose (cGy) 645.4 966.0 0.26
mean value of (D95*/prescription dose) for PTV1 (−) 0.97 0.98 0.70
mean value of (D95*/prescription dose) for PTV2 (−) 0.97 0.98 0.48
  1. *D95: dose delivered to ≥ 95% of reference volume PTV1 or PTV2.