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Table 3 Association of clinical factors and the risk of acute skin and oral mucosa reactions

From: XRCC1 codon 399Gln polymorphism is associated with radiotherapy-induced acute dermatitis and mucositis in nasopharyngeal carcinoma patients

 

Dermatitis

 

Mucositis

 
 

Grade 1–2

Grade 3

pvalue

Grade 1–2

Grade 3

p value

Age (year)

Mean±SD

49.3±12.3

50.8±10.2

0.587

48.2±12.5

51.5±10.7

0.144

Gender

      

Male

61

17

0.775

48

30

0.246

Female

29

7

 

18

18

 

Drinking

      

Yes

8

1

0.737

4

5

0.617

No

82

23

 

62

43

 

Smoking

      

Yes

49

12

0.698

36

25

0.795

No

41

12

 

30

23

 

Body mass index

≤25

73

20

1.00

55

38

0.571

>25

17

4

 

11

10

 

T-staging

T1

8

1

0.418

5

4

0.474

T2

27

5

 

22

10

 

T3

29

7

 

18

18

 

T4

26

11

 

21

16

 

N-staging

N0

10

0

0.240

8

2

0.219

N1

19

5

 

12

12

 

N2

46

12

 

36

22

 

N3

15

7

 

10

12

 

Chemotherapy

Yes

77

21

1.00

55

43

0.343

No

13

3

 

11

5

 

Radiotherapy technique

3D-CRT

40

8

0.327

29

19

0.642

IMRT

50

16

 

37

29

 

Irradiation Dose (Gy)

Mean±SD

42.37±5.09

43.16±4.43

0.493

29.48±10.16

30.92±10.38

0.460

  1. Abbreviations: IMRT = intensity-modulated radiotherapy; 3D-CRT = three-dimensional conformal radiation therapy, SD = Standard deviation. Gy=Gray.