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Table 3 Association of clinical factors and the risk of acute skin and oral mucosa reactions

From: XRCC1 codon 399Gln polymorphism is associated with radiotherapy-induced acute dermatitis and mucositis in nasopharyngeal carcinoma patients

  Dermatitis   Mucositis  
  Grade 1–2 Grade 3 pvalue Grade 1–2 Grade 3 p value
Age (year)
Mean±SD 49.3±12.3 50.8±10.2 0.587 48.2±12.5 51.5±10.7 0.144
Gender       
Male 61 17 0.775 48 30 0.246
Female 29 7   18 18  
Drinking       
Yes 8 1 0.737 4 5 0.617
No 82 23   62 43  
Smoking       
Yes 49 12 0.698 36 25 0.795
No 41 12   30 23  
Body mass index
≤25 73 20 1.00 55 38 0.571
>25 17 4   11 10  
T-staging
T1 8 1 0.418 5 4 0.474
T2 27 5   22 10  
T3 29 7   18 18  
T4 26 11   21 16  
N-staging
N0 10 0 0.240 8 2 0.219
N1 19 5   12 12  
N2 46 12   36 22  
N3 15 7   10 12  
Chemotherapy
Yes 77 21 1.00 55 43 0.343
No 13 3   11 5  
Radiotherapy technique
3D-CRT 40 8 0.327 29 19 0.642
IMRT 50 16   37 29  
Irradiation Dose (Gy)
Mean±SD 42.37±5.09 43.16±4.43 0.493 29.48±10.16 30.92±10.38 0.460
  1. Abbreviations: IMRT = intensity-modulated radiotherapy; 3D-CRT = three-dimensional conformal radiation therapy, SD = Standard deviation. Gy=Gray.