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Table 2 Association of polymorphisms in XRCC1 and the risk of acute oral mucositis

From: XRCC1 codon 399Gln polymorphism is associated with radiotherapy-induced acute dermatitis and mucositis in nasopharyngeal carcinoma patients

 

Mucositis

  

Genotype

Grade 1–2

Grade 3

OR (95% CI)

p value

XRCC1 (194Arg/Trp)

    

Arg/Arg (wild-type)

31

24

1.00 (ref)

 

Arg/Trp

33

19

0.744 (0.342–1.62)

0.454

Trp/Trp

2

5

NC

NC

XRCC1 (399Arg/Gln)

    

Arg/Arg (wild-type)

40

23

1.00 (ref)

 

Arg/Gln

19

23

2.11 (0.951–4.66)

0.065

Gln/Gln

7

2

NC

NC

  1. Abbreviations: ref = reference; NC = not calculated; OR = Odds ratio; CI = confidence interval.
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Radiation Oncology

ISSN: 1748-717X

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