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Table 4 Baseline clinical characteristics of first 132consecutive study patients from each technique group

From: Comparison between preoperative and real-time intraoperative planning 125I permanent prostate brachytherapy: long-term clinical biochemical outcome

Characteristics Total sample Implant technique P value
   PP IoP
  (n =264) (n =132) (n = 132)
Age, years     
      Mean (SD) 67.7 (5.8) 67.9 (6.0) 67.4 (5.7)  
      Median 68.0 68.0 68.0  
      Range 50.0–83.0 50.0–83.0 52.0–78.0  
      95% CI 66.9–68.4 66.9–68.9 66.4–68.4 0.6*
PSA, ng/ml     
      Mean (SD) 8.2 (3.4) 8.6 (3.7) 7.8 (3.1)  
      Median 7.6 7.6 7.5  
      Range 0.7–20.0 0.7–20.0 0.8–17.0  
      95% CI 7.8–8.6 7.9–9.2 7.3–8.3 0.1*
PSA, n (%)     
      ≤ 10 201 (76.1) 94 (71.2) 107 (81.1)  
      > 10 63 (23.9) 38 (28.8) 25 (18.9) 0.06**
Gleason score,     
      Mean (SD) 5.5 (0.9) 5.3 (0.9) 5.7 (0.8)  
      Median 6.0 5.0 6.0  
      Range 1.0–7.0 2.0–7.0 1.0–7.0  
      95% CI 5.4–5.6 5.1–5.4 5.6–5.8 <0.001*
Gleason score < 7, n (%) 248 (93.9) 128 (97) 120 (90.9) 0.07**
Clinical stage, n (%)     
      T1-T2a 225 (90.7) 113 (89.0) 112 (92.6)  
      > T2a 23 (9.3) 14 (11.0) 9 (7.4) 0.3**
ADT, n (%) 112 (42.4) 54 (40.9) 58 (43.9) 0.6**
EBRT, n (%) 16 (6.1) 4 (3) 12 (9.1) 0.07**
Follow-up, months     
      Mean (SD) 83.3(39.6) 80.5 (43.5) 86.2 (35.2)  
      Median 84.0 83.0 95.5  
      Range 3.0–155.0 3.0–155.0 7.0–132.0  
      95% CI 78.5–88.1 72.9–87.9 80.2–92.3 0.4*
  1. * Mann–Whitney test; ** Chi-square test.
  2. PP, Preplanning; IoP, Intraoperative planning; PSA, Prostate-specific antigen ADT, Androgen deprivation therapy; EBRT, External beam radiation.