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Table 2 Risk factors for locoregional recurrence (LR) and distant metastasis (DM) in patients with resected N1 non–small cell lung cancer (NSCLC)

From: Risk factors for locoregional recurrence in patients with resected N1 non-small cell lung cancer: a retrospective study to identify patterns of failure and implications for adjuvant radiotherapy

Author n CT (%) 5-yr actuarial DM (%) 5-yr actuarial LR (%) Risk factors for LR
Saynak[34] 335 8 23 (crude) 35 LVI; tumor size
Higgins[36] 198 25 55 40 Visceral pleural invasion; VATS approach; no. of involved N1 nodes
Varlotto[38] 60 40 32 46 Chemotherapy
Sawyer[30] 107 0 47 38 Positive preoperative bronchoscopy findings
Lopez Guerra[33] 1402 9 16 9 Surgical procedure; LVI; visceral pleural invasion; tumor size
Fujimoto[37] 180 NM 23 (crude) 22 (crude) Visceral pleural invasion
This study 199 79.4 42.6 22.7 Incomplete MLN dissection; positive LN at station 10
  1. LR, locoregional recurrence; DM, distant metastasis; LVI, lymphovascular invasion; VATS, video-assisted thoracic surgery; LN, lymph node; MLN, mediastinal lymph node; NM, not mentioned.
  2. Comparisons between LR and DM rates for previously reported risk factors and those reported in our study.