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Table 2 Relationship between MLD and early lung toxicity in 3D-CRT for BC in world literature

From: Meta-analysis of incidence of early lung toxicity in 3-dimensional conformal irradiation of breast carcinomas

Author, Year of data collection

Country

n

RP endpoint

Test type,

p value

Perh Lind et al. 1994– 1998 [17]

Sweden

475

Clinical RP CTC-NCIC

Gamma statistics G = 0.669

<0.001

Zsusana Kahan et al. 2001–2004 [31]

Hungary

119

Radiological RP – CTC 2.0

Student’s t-test (RP + vs RP-)

0.003

Javier Jaen et al. 2002 [44]

Spain

39

Change in perfused volume (%)

Correlation coefficient, r = −0.447

0.013

  1. RP radiation pneumonitis, n number of patients, CTC/CTC-NCIC common toxicity criteria, RT radiotherapy, MLD mean lung dose.