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Table 6 Summary of the average DVH parameters in total dose (Gy) of the CV treatment technique, compared to other published values

From: Equivalence of Gyn GEC-ESTRO guidelines for image guided cervical brachytherapy with EUD-based dose prescription

DVH parameter

CV

Georg et al.[9]

Georg et al.[10]

Levitchi et al.[33]

Jürgenliemk-Schulz et al.[38]

Jürgenliemk-Schulz et al.[39]

Nesvacil et al.[40]

Lindegaard et al.[41]

Method

HDR

HDR

HDR

PDR

PDR

HDR/PDR

HDR

PDR

Rectum

        

D0.1 cc

79 ± 1

88 ± 10*

83 - 132 a

83 b

    
  

81 ± 13**

86 ± 27**

65 ± 15**

   

74 ± 9**

D1cc

72 ± 2

76 ± 7*

71 - 87 a

     
  

70 ± 9**

69 ± 14**

    

69 ± 6**

D2cc

70 ± 2

72 ± 6*

67 - 78 a

68 b

    
  

66 ± 8**

65 ± 12**

57 ± 8**

66 ± 6**

54 ± 2** c

57 ± 6**

67 ± 6**

      

69 ± 2** d

  

Bladder

        

D0.1 cc

100 ± 3

 

61 - 178 a

109 b

    
   

162 ± 75**

78 ± 22**

   

86 ± 12**

D1cc

86 ± 3

 

71 - 116 a

     
   

108 ± 31**

    

77 ± 8**

D2cc

81 ± 3

 

70 – 101 a

72 b

81 ± 6**

53 ± 2** c

76 ± 9**

 
   

95 ± 22**

64 ± 11**

 

101 ± 11** d

 

73 ± 6**

  1. Abbreviations: SD standard deviation, HDR high dose rate, PDR pulsed dose rate.
  2. *Clinical symptoms (LENT/SOMA) score 1–4 and Rectoscopic changes (VRS) score 3–5.
  3. **Population average; no interstitial needles.
  4. a5% - 10% probability of G2-G4 side effects (dose range not shown).
  5. bApproximately 10% probability of G2-G4 toxicity (dose range not shown).
  6. cSmall volume tumor.
  7. dLarge volume tumor.