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Table 3 Comparison of OARs’ doses calculated from PVP, HAP and non-enhanced CTs

From: Hepatic arterial phase and portal venous phase computed tomography for dose calculation of stereotactic body radiation therapy plans in liver cancer: a dosimetric comparison study

  Dp Da Dn P(p,a,n)* (Dn-Dp)/Dn (%) P(p,n)# (Dn-Da)/Dn (%) P(a,n)# (Da-Dp)/Dn (%) P(p,a)#
3D-CRT           
Liver V21 (%) 12.77 ± 11.45 12.87 ± 11.53 12.94 ± 11.55 0.000 1.70 ± 1.50 0.000 0.90 ± 1.20 0.000 0.80 ± 0.85 0.000
Liver Dmean (Gy) 8.52 ± 5.00 8.57 ± 5.03 8.61 ± 5.04 0.000 1.02 ± 0.73 0.000 0.51 ± 0.64 0.000 0.52 ± 0.47 0.000
Right kidney D2%(Gy) 13.59 ± 14.36 13.60 ± 14.35 13.69 ± 14.48 0.000 0.56 ± 1.29 0.000 0.33 ± 1.10 0.001 0.23 ± 0.58 0.140
Right kidney Dmean (Gy) 2.87 ± 3.47 2.87 ± 3.47 2.89 ± 3.50 0.201 -0.09 ± 1.01 - 0.18 ± 0.81 - -0.27 ± 0.53 -
Bowl D2% (Gy) 12.83 ± 8.63 12.84 ± 8.65 12.86 ± 8.72 0.040 -0.31 ± 2.50 0.254 -0.13 ± 2.27 0.074 -0.18 ± 1.13 0.268
Stomach D2% (Gy) 16.42 ± 7.62 16.54 ± 7.66 16.65 ± 7.69 0.000 1.45 ± 2.33 0.003 0.71 ± 1.40 0.004 0.74 ± 1.31 0.001
Spinal cord D2% (Gy) 11.28 ± 6.79 11.31 ± 6.79 11.36 ± 6.81 0.006 0.73 ± 1.38 0.000 0.46 ± 0.88 0.004 0.27 ± 1.06 0.234
IMRT           
Liver V21 (%) 25.31 ± 6.90 25.35 ± 6.89 25.39 ± 6.87 0.040 0.38 ± 0.87 0.046 0.19 ± 0.68 0.338 0.19 ± 0.43 0.026
Liver Dmean (Gy) 10.00 ± 4.95 10.05 ± 4.99 10.09 ± 4.99 0.000 0.97 ± 0.77 0.000 0.49 ± 0.74 0.000 0.48 ± 0.46 0.000
Right kidney D2% (Gy) 14.71 ± 14.88 14.71 ± 14.89 14.82 ± 15.02 0.003 0.32 ± 1.22 0.002 0.30 ± 1.21 0.006 0.01 ± 0.50 0.050
Right kidney Dmean (Gy) 3.04 ± 3.12 3.03 ± 3.12 3.06 ± 3.15 0.090 0.02 ± 1.00 - 0.29 ± 0.84 - -0.27 ± 0.54 -
Bowl D2% (Gy) 10.99 ± 6.88 11.02 ± 6.90 11.09 ± 6.93 0.000 0.90 ± 0.86 0.000 0.65 ± 0.88 0.002 0.26 ± 0.69 0.178
Stomach D2% (Gy) 11.73 ± 6.99 11.80 ± 7.03 11.85 ± 7.07 0.000 0.89 ± 1.90 0.012 0.39 ± 1.23 0.008 0.50 ± 1.28 0.002
Spinal cord D2% (Gy) 9.09 ± 4.50 9.12 ± 4.49 9.17 ± 4.50 0.003 0.99 ± 1.64 0.003 0.57 ± 1.13 0.001 0.42 ± 0.95 0.195
VMAT           
Liver V21 (%) 20.71 ± 7.27 20.75 ± 7.27 20.77 ± 7.26 0.017 0.35 ± 0.71 0.018 0.14 ± 0.47 0.355 0.21 ± 0.34 0.005
Liver Dmean (Gy) 10.10 ± 5.24 10.16 ± 5.28 10.20 ± 5.29 0.000 0.97 ± 0.67 0.000 0.45 ± 0.59 0.000 0.52 ± 0.43 0.000
Right kidney D2% (Gy) 14.30 ± 14.80 14.33 ± 14.83 14.41 ± 14.87 0.000 0.68 ± 1.08 0.000 0.38 ± 0.89 0.000 0.31 ± 0.48 0.000
Right kidney Dmean (Gy) 3.34 ± 3.55 3.34 ± 3.55 3.36 ± 3.56 0.187 -0.03 ± 1.03 - 0.14 ± 0.76 - -0.17 ± 0.41 -
Bowl D2% (Gy) 11.87 ± 7.28 11.90 ± 7.32 11.98 ± 7.35 0.000 0.95 ± 0.87 0.000 0.81 ± 1.02 0.001 0.14 ± 0.94 0.206
Stomach D2% (Gy) 11.53 ± 8.30 11.65 ± 8.47 11.65 ± 8.40 0.000 0.78 ± 1.60 0.001 0.08 ± 1.95 0.031 0.70 ± 1.12 0.000
Spinal cord D2% (Gy) 9.92 ± 3.79 9.93 ± 3.79 9.95 ± 3.80 0.013 0.24 ± 1.18 0.010 0.21 ± 0.56 0.031 0.04 ± 0.77 0.081
  1. Abbrevations: V21, the percentage liver volume received more than 21 Gy; Dmean, the mean dose; D2%, the minimum absorbed dose that covers 2% of the volume of a certain OAR. The others as in Table 2. *, Friedman test; #, Wilcoxon signed ranks test.