Table 3 Grade 1-4 RON in 21/356 patients at risk (oropharynx or oral cavity tumors irradiated with >60Gy to the mandible): 5 with grade 3/4 RON, 3/5 following invasive procedures post-IMRT
From: Late term tolerance in head neck cancer patients irradiated in the IMRT era
RON, initial G | RON therapy (n) | Outcome(n): G | Complications(n) following RON therapy: final G | Onset post IMRT months | IMRT sequence |
|---|---|---|---|---|---|
G1-2 | no therapy, spontaneous healing (2) | G0 | None: G0 | 5/21 | 2 definitive |
debridment + antibiotics (4)* | ad integrum healing (4/4): G0 | None: G0 | 5/6/12 | 3 postop, 1 definitive | |
G2-3 | partial decortication (11)** | ad integrum healing (10/11)**: G0 | pathol. fracture, chronic infection (1/11): G4 | 3 (0-12) | 6 postop, 5 definitive |
G3 | partial mandibulectomy (4) | ad integrum healing (1): G3 | pathol. fracture (1/4) ***: G4 | 6/6/18/28*** | 3 postop***, 1 definitive |
osteomyelitis (1/4) ***: G4 | |||||
osteocutaneous fistula (1/4)***: G4 |