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Table 3 Predictive factors associated with clinical complete remission to radiotherapy (43 lesions analyzed using the GEE model)

From: Clinicopathologic features and responses to radiotherapy of myeloid sarcoma

Characteristics

Complete response (No. of patients)

Partial response and stable disease (No. of patients)

Complete response rate

Univariate odds ratio

95% Confidence interval

P-value

BED dose

      

≥22 Gy

6

4

60%

1.15

0.20-6.63

0.88

<22 Gy

21

12

63.64%

1 (Referent)

  

Underlying disease

      

Non-AML

3

6

33.33%

5.436

0.999-29.578

0.050

AML

24

10

70.59%

1 (Referent)

  

Age

      

≥50 y

9

5

64.29%

2.92

0.47-18.14

0.25

<50 y

18

11

62.07%

1 (Referent)

  

Gender

      

Female

7

5

58.33%

1.41

0.31-6.36

0.65

Male

20

11

64.52%

1 (Referent)

  

Cytogenetics

      

Abnormal

13

10

56.52%

1.35

0.27-6.83

0.72

Normal

14

6

70%

1 (Referent)

  

Previous BMT before RT

      

Yes

16

2

88.89%

0.10

0.01-1.14

0.06

No

11

14

44%

1 (Referent)

  

BM involvement at GS RT

      

Yes

16

8

66.67%

1.51

0.23-9.82

0.67

No

11

8

57.89%

1 (Referent)

  
  1. Abbreviations: CR, complete remission; PR, partial response; SD, stable disease; RT, radiotherapy; BMT, bone marrow transplant; BM, bone marrow.