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Table 2 Predictive factors associated with clinical CR to radiotherapy (n = 20)

From: Clinicopathologic features and responses to radiotherapy of myeloid sarcoma

Characteristics Complete response (No. of patients) Partial response and stable disease (No. of patients) Complete response rate Crude odds ratio 95% Confidence interval P-value*
BED dose       
≥22 Gy 3 4 43% 4.44 0.62-32.07 0.14
<22 Gy 10 3 77% 1 (Referent)   
Underlying disease       
Non-AML 3 4 43% 4.44 0.62-32.07 0.17
AML 10 3 77% 1 (Referent)   
Age       
≥50 y 3 5 37.5% 8.33 1.03-67.14 0.06
<50 y 10 2 83.3% 1 (Referent)   
Gender       
Female 5 4 55.6% 2.13 0.33-13.81 0.64
Male 8 3 72.7% 1 (Referent)   
Cytogenetics       
Abnormal 6 4 60% 1.56 0.24-9.91 1
Normal 7 3 70% 1 (Referent)   
Previous BMT before RT       
Yes 6 0 100% NA NA 0.05
No 7 7 50% 1 (Referent)   
BM involvement at GS RT       
Yes 8 5 61.5% 1.56 0.22-11.37 1
No 5 2 71% 1 (Referent)   
  1. Abbreviations: CR, complete remission; PR, partial response; SD, stable disease, BMT, bone marrow transplant; RT, radiotherapy; BM, bone marrow.
  2. *Fisher’s exact test.