Skip to main content

Table 3 Dosimetric comparison of normal tissues in all four radiotherapy plan groups (Gy)

From: Single arc volumetric-modulated arc therapy is sufficient for nasopharyngeal carcinoma: a dosimetric comparison with dual arc VMAT and dynamic MLC and step-and-shoot intensity-modulated radiotherapy

 

VMAT1

VMAT2

dIMRT

ssIMRT

p GLM-u

p VMAT1

p VMAT1

p VMAT1

p VMAT2

p VMAT2

p dIMRT

     

-VMAT2

-dIMRT

-ssIMRT

-dIMRT

-ssIMRT

-ssIMRT

Brain stem

D2%

41.21 ± 0.92

41.94 ± 0.42

42.56 ± 0.48

46.32 ± 0.44

0.024

0.679

0.444

0.005

0.724

0.015

0.036

Dmean

24.02 ± 2.58

23.46 ± 3.97

24.85 ± 3.86

27.51 ± 0.41

<0.001

0.326

0.056

<0.001

0.117

<0.001

<0.001

Spinal-cord

D2%

35.15 ± 1.75

32.59 ± 2.91

33.60 ± 2.67

28.66 ± 3.02

<0.001

0.001

0.073

<0.001

0.160

<0.001

<0.001

Dmean

26.26 ± 2.66

23.46 ± 2.74

25.01 ± 2.79

22.3 ± 3.52

<0.001

<0.001

0.055

<0.001

0.017

0.071

0.001

Chiasm

Dmax

47.51 ± 4.52

47.89 ± 5.01

47.17 ± 5.83

48.23 ± 6.32

0.600

      

Dmean

34.44 ± 6.88

36.38 ± 5.79

35.30 ± 5.46

36.37 ± 7.30

0.013

0.033

0.427

0.023

0.330

0.988

0.337

Optic N L

Dmax

43.73 ± 10.41

46.20 ± 9.77

44.13 ± 9.52

45.11 ± 10.00

0.177

      

Dmean

24.17 ± 9.69

26.17 ± 9.69

24.40 ± 8.29

26.22 ± 9.24

0.022

0.021

0.787

0.018

0.07

0.955

0.065

Optic N R

Dmax

43.30 ± 11.85

44.88 ± 9.57

42.04 ± 10.18

44.84 ± 8.91

0.048

0.177

0.278

0.188

0.017

0.971

0.018

Dmean

25.04 ± 9.69

25.66 ± 9.53

23.92 ± 8.74

26.04 ± 9.15

0.076

      

Lens L

Dmean

3.86 ± 1.35

4.13 ± 1.49

4.18 ± 1.38

5.18 ± 1.53

<0.001

0.111

0.06

<0.001

0.767

<0.001

<0.001

Lens R

Dmean

3.71 ± 1.05

4.35 ± 1.7

4.21 ± 1.21

5.22 ± 1.38

<0.001

0.004

0.022

<0.001

0.535

<0.001

<0.001

Parotid L

D50%

28.45 ± 4.20

27.04 ± 4.99

23.89 ± 4.05

26.73 ± 4.09

<0.001

0.064

<0.001

0.025

<0.001

0.682

<0.001

Dmean

32.20 ± 3.30

31.57 ± 3.86

29.01 ± 3.31

31.48 ± 3.21

<0.001

0.223

<0.001

0.165

<0.001

0.863

<0.001

Parotid R

D50%

31.73 ± 5.88

28.18 ± 5.38

25.42 ± 5.53

27.07 ± 3.79

<0.001

0.001

<0.001

<0.001

0.008

0.273

0.104

Dmean

34.14 ± 3.56

32.47 ± 3.83

30.11 ± 3.93

31.65 ± 3.08

<0.001

0.085

<0.001

0.001

0.001

0.238

0.097

Oral cavity

Dmean

40.35 ± 4.77

36.99 ± 6.18

41.42 ± 6.77

43.21 ± 5.60

<0.001

<0.001

0.230

0.002

<0.001

<0.001

0.049

Larynx

Dmean

37.67 ± 4.13

35.17 ± 4.55

35.86 ± 3.05

34.76 ± 3.82

<0.001

0.001

0.003

<0.001

0.249

0.395

0.048

  1. GLM-u: general linear model-univariate; VMAT1: single arc VMAT, VMAT2: dual arc VMAT; dIMRT: dynamic MLC IMRT; ssIMRT: step-and-shoot IMRT. Lens L, left lens; Lens R, right lens; Optic L, left optic nerve; Optic R, right optic nerve; Parotid L, left parotid; Parotid R, right parotid. “Bold numbers” means that p value has a statistically significance.
Back to article page

Radiation Oncology

ISSN: 1748-717X

Contact us