Figure 3
From: MiR-34a is up-regulated in response to low dose, low energy X-ray induced DNA damage in breast cells
Percentage of cells containing apoptotic features, observed by fluorescent microscopy (1000x) after Hoechst staining. (A) MCF-10A and (B) MCF-7 cell lines 4 and 24 hours after 0.003; 0.012; 0.048 Gy/28 kV and 5 Gy/30 Kv X-ray irradiation (C) Example of an apoptotic cell displaying a perturbation in its nuclear envelope. Paired t-test with 95% confidence intervals were performed on the irradiated samples of each type of cell line in comparison to its corresponding mock control. (Student’s t test * P ≤ 0.05; ** P ≤ 0.001).