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Table 2 Dosimetry comparisons of serial structures and parallel structures

From: Using neoadjuvant chemotherapy and replanning intensity-modulated radiotherapy for nasopharyngeal carcinoma with intracranial invasion to protect critical normal tissue

Variable Replanned Not replanned P value Variable Replanned Not replanned P value
Brain stem Temporal lobe
D1 (Gy) 56.45 ± 3.33 57.31 ± 5.65 0.209 D-Mean (Gy) 20.20 ± 3.26 21.48 ± 3.86 0.000
D5 (Gy) 52.76 ± 3.28 54.09 ± 4.34 0.001 D50 (Gy) 14.87 ± 4.75 16.05 ± 5.23 0.000
D10 (Gy) 50.38 ± 3.36 51.40 ± 4.36 0.023 D80 (Gy) 6.53 ± 2.66 6.96 ± 2.88 0.000
Optic chiasm Inner ear
D1 (Gy) 58.55 ± 7.79 62.76 ± 7.64 0.000 D-Mean (Gy) 52.96 ± 4.94 53.41 ± 5.23 0.018
D5 (Gy) 57.86 ± 7.63 62.00 ± 7.47 0.000 D-50 (Gy) 52.83 ± 5.34 53.98 ± 5.81 0.009
D10 (Gy) 57.41 ± 7.66 61.30 ± 7.58 0.000 D-80 (Gy) 45.82 ± 5.43 46.28 ± 5.73 0.030
Optic nerve Middle ear
D1 (Gy) 57.77 ± 8.95 61.74 ± 8.45 0.000 D-Mean (Gy) 59.24 ± 5.53 59.51 ± 5.76 0.097
D5 (Gy) 56.31 ± 8.96 60.29 ± 8.49 0.000 D-50 (Gy) 59.52 ± 5.81 60.00 ± 6.09 0.009
D10 (Gy) 54.83 ± 9.15 58.75 ± 8.72 0.000 D-80 (Gy) 54.39 ± 6.71 54.79 ± 6.97 0.027
  1. Abbreviations: D1 dose to 1% of the volume, D5 dose to 5% of the volume, D10 dose to 10% of the volume, D50 dose to 50% of the volume, D80 dose to 80% of the volume, Dmean mean dose per fraction.