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Table 2 Dosimetry comparisons of serial structures and parallel structures

From: Using neoadjuvant chemotherapy and replanning intensity-modulated radiotherapy for nasopharyngeal carcinoma with intracranial invasion to protect critical normal tissue

Variable

Replanned

Not replanned

P value

Variable

Replanned

Not replanned

P value

Brain stem

Temporal lobe

D1 (Gy)

56.45 ± 3.33

57.31 ± 5.65

0.209

D-Mean (Gy)

20.20 ± 3.26

21.48 ± 3.86

0.000

D5 (Gy)

52.76 ± 3.28

54.09 ± 4.34

0.001

D50 (Gy)

14.87 ± 4.75

16.05 ± 5.23

0.000

D10 (Gy)

50.38 ± 3.36

51.40 ± 4.36

0.023

D80 (Gy)

6.53 ± 2.66

6.96 ± 2.88

0.000

Optic chiasm

Inner ear

D1 (Gy)

58.55 ± 7.79

62.76 ± 7.64

0.000

D-Mean (Gy)

52.96 ± 4.94

53.41 ± 5.23

0.018

D5 (Gy)

57.86 ± 7.63

62.00 ± 7.47

0.000

D-50 (Gy)

52.83 ± 5.34

53.98 ± 5.81

0.009

D10 (Gy)

57.41 ± 7.66

61.30 ± 7.58

0.000

D-80 (Gy)

45.82 ± 5.43

46.28 ± 5.73

0.030

Optic nerve

Middle ear

D1 (Gy)

57.77 ± 8.95

61.74 ± 8.45

0.000

D-Mean (Gy)

59.24 ± 5.53

59.51 ± 5.76

0.097

D5 (Gy)

56.31 ± 8.96

60.29 ± 8.49

0.000

D-50 (Gy)

59.52 ± 5.81

60.00 ± 6.09

0.009

D10 (Gy)

54.83 ± 9.15

58.75 ± 8.72

0.000

D-80 (Gy)

54.39 ± 6.71

54.79 ± 6.97

0.027

  1. Abbreviations: D1 dose to 1% of the volume, D5 dose to 5% of the volume, D10 dose to 10% of the volume, D50 dose to 50% of the volume, D80 dose to 80% of the volume, Dmean mean dose per fraction.