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Table 1 In vitro radiobiological parameters of LS180 cells (mean ± SD)

From: Combined effects of C225 and 125-iodine seed radiation on colorectal cancer cells

 

125I-CLDR

C225 + 125I-CLDR

D0(Gy)

1.20 ± 0.15

0.86 ± 0.03

Dq(Gy)

0.62 ± 0.30

0.54 ± 0.06

N

1.67 ± 0.31

1.88 ± 0.10

SF2

0.30 ± 0.04

0.18 ± 0.01

  1. The values for D0, Dq, and N were determined using the single-hit multitarget model. d = D0 (125I - CLDR)/D0 (C225 + 125I-CLDR). D0, Mean inactivation dose; Dq, Quasi-threshold dose; N, extrapolation number; SF2, Survival fraction at 2 Gy.
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Radiation Oncology

ISSN: 1748-717X

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