Figure 5
From: Combined effects of C225 and 125-iodine seed radiation on colorectal cancer cells
C225 inhibits the activation of Akt and Erk when combined with radiation. (A) Immunoblotting of some proteins involving in EGFR signaling pathways at the end of treatment (0 h), the exposure dose was 4 Gy. Cells were lysed immediately after treatment. Representative analysis of the protein levels of EGFR (B), phosphorylated Akt (C), and phosphorylated Erk (D). All data represent three independent experiments, mean ± SD. Unpaired t test was used for data analysis.