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Table 4 Local-regional control and survival

From: Outcomes and patterns of care of patients with locally advanced oropharyngeal carcinoma treated in the early 21st century

 

5-year local-regional control

p- value*

5-year overall survival

p- value*

Age in years

    

Continuous variable

 

.136

 

<.001

Sex

 

.896

 

.438

 Male

87%

 

79%

 

 Female

87%

 

77%

 

Race

 

.091

 

.261

 White

88%

 

81%

 

 Non-white

76%

 

62%

 

Smoke

 

.002

 

<.001

 Current

75%

 

60%

 

 Former

88%

 

80%

 

 Never

92%

 

88%

 

Primary site

 

.006

 

<.001

 Tonsil

91%

 

83%

 

 Base of tongue

86%

 

80%

 

 Other

65%

 

43%

 

T-category

 

<.001

 

<.001

 1-2

94%

 

90%

 

 3-4

75%

 

60%

 

N-category

 

.446

 

.001

 0

74%

 

65%

 

 1 -2a

93%

 

86%

 

 2b – 2c

86%

 

79%

 

 3

80%

 

59%

 

Lowest neck level

 

.529

 

.498

 0

74%

 

67%

 

 2

90%

 

83%

 

 3

86%

 

77%

 

 4

76%

 

67%

 

Treatment

 

.454

 

.027

 XRT alone

92%

 

86%

 

 CTXRT

82%

 

72%

 

 Ind. CTX > XRT

89%

 

84%

 

 Ind. CTX > CTXRT

81%

 

71%

 

Radiation technique

 

.003

 

.084

 IMRT

92%

 

84%

 

 3D conformal

77%

 

66%

 

Radiation Fractionation

 

.414

 

.150

 Once- daily

90%

 

83%

 

 Altered fractionation

81%

 

70%

 
  1. *multivariable analysis; XRT – Radiotherapy; CTXRT – concurrent chemoradiation; Ind. CTX – Induction chemotherapy.