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Table 4 Local-regional control and survival

From: Outcomes and patterns of care of patients with locally advanced oropharyngeal carcinoma treated in the early 21st century

  5-year local-regional control p- value* 5-year overall survival p- value*
Age in years     
Continuous variable   .136   <.001
Sex   .896   .438
 Male 87%   79%  
 Female 87%   77%  
Race   .091   .261
 White 88%   81%  
 Non-white 76%   62%  
Smoke   .002   <.001
 Current 75%   60%  
 Former 88%   80%  
 Never 92%   88%  
Primary site   .006   <.001
 Tonsil 91%   83%  
 Base of tongue 86%   80%  
 Other 65%   43%  
T-category   <.001   <.001
 1-2 94%   90%  
 3-4 75%   60%  
N-category   .446   .001
 0 74%   65%  
 1 -2a 93%   86%  
 2b – 2c 86%   79%  
 3 80%   59%  
Lowest neck level   .529   .498
 0 74%   67%  
 2 90%   83%  
 3 86%   77%  
 4 76%   67%  
Treatment   .454   .027
 XRT alone 92%   86%  
 CTXRT 82%   72%  
 Ind. CTX > XRT 89%   84%  
 Ind. CTX > CTXRT 81%   71%  
Radiation technique   .003   .084
 IMRT 92%   84%  
 3D conformal 77%   66%  
Radiation Fractionation   .414   .150
 Once- daily 90%   83%  
 Altered fractionation 81%   70%  
  1. *multivariable analysis; XRT – Radiotherapy; CTXRT – concurrent chemoradiation; Ind. CTX – Induction chemotherapy.