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Table 2 Patient demographics and treatment

From: Outcomes and patterns of care of patients with locally advanced oropharyngeal carcinoma treated in the early 21st century

 

All (N= 1046) No. (%)

Current smokers (N= 242) No. (%)

Former smokers (N= 381) No. (%)

Never smokers (N= 423) No. (%)

p- value

Age in years

     

 Mean (range)

56.2 (28–87)

55.6 (35 – 80)

59.3 (36 – 87)

53.7 (28 – 81)

.01

 Median

55

55

58

53

 

Sex

    

.725

 Male

906 (87)

207 (86)

334 (88)

365 (86)

 

 Female

140 (13)

35 (14)

47 (12)

58 (14)

 

Race

    

<.001

 White

930 (89)

197 (21)

353 (38)

380 (41)

 

 Black

47 (5)

29 (62)

3 (6)

15 (32)

 

 Hispanic

55 (5)

12 (22)

19 (35)

24 (44)

 

 Other

14 (1)

5 (36)

6 (43)

3 (21)

 

Cigarette pack-year

    

<.001

 None

423 (42)

  

423 (100)

 

 1 - 30

339 (32)

86 (36)

253 (69)

  

 >30

265 (26)

153 (64)

112 (31)

  

Primary site

    

<.001

 Tonsil

460 (44)

111 (46)

171 (45)

178 (42)

 

 Base of tongue

511 (49)

95 (39)

186 (49)

230 (54)

 

 Other*

75 (7)

36 (15)

24 (6)

15 (4)

 

T-category

    

<.001

 1-2

640 (62)

107 (44)

235 (62)

298 (71)

 

 3-4

406 (38)

135 (56)

146 (38)

125 (30)

 

N-category

    

.07

 0

57 (5)

20 (8)

22 (6)

15 (4)

 

 1 -2a

317 (30)

63 (26)

120 (31)

134 (32)

 

 2b – 2c

573 (55)

128 (53)

205 (54)

240 (57)

 

 3

99 (9)

31 (13)

34 (9)

34 (8)

 

Stage

    

.001

 3

206 (20)

43 (18)

83 (22)

80 (19)

 

 4A

707 (68)

149 (62)

257 (68)

30 (72)

 

 4B

133 (13)

50 (21)

41 (11)

42 (10)

 

Treatment

    

.176

 XRT alone

415 (40)

83 (34)

158 (42)

175 (41)

 

 CTXRT

389 (37)

102 (43)

146 (38)

141 (33)

 

 Ind. CTX > XRT

118 (11)

29 (12)

35 (9)

53 (13)

 

 Ind. CTX > CTXRT

124 (12)

28 (12)

42 (11)

54 (14)

 

Radiation technique

    

<.001

 IMRT

714 (69)

141 (58)

211 (69)

316 (75)

 

 3D conformal

328 (31)

101 (42)

120 (31)

107 (25)

 

Radiation Fractionation

    

.442

 Once- daily

700 (67)

154 (64)

250 (66)

296 (70)

 

 Altered fractionation

346 (33)

88 (36)

131 (34)

127 (30)

 
  1. *Other primary sites: soft palate, 19 patients; pharyngeal wall, 34, NOS (not otherwise specified), 22.
  2. XRT – Radiotherapy; CTXRT – concurrent chemoradiation; Ind. CTX – Induction chemotherapy.