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Table 2 Patient demographics and treatment

From: Outcomes and patterns of care of patients with locally advanced oropharyngeal carcinoma treated in the early 21st century

  All (N= 1046) No. (%) Current smokers (N= 242) No. (%) Former smokers (N= 381) No. (%) Never smokers (N= 423) No. (%) p- value
Age in years      
 Mean (range) 56.2 (28–87) 55.6 (35 – 80) 59.3 (36 – 87) 53.7 (28 – 81) .01
 Median 55 55 58 53  
Sex      .725
 Male 906 (87) 207 (86) 334 (88) 365 (86)  
 Female 140 (13) 35 (14) 47 (12) 58 (14)  
Race      <.001
 White 930 (89) 197 (21) 353 (38) 380 (41)  
 Black 47 (5) 29 (62) 3 (6) 15 (32)  
 Hispanic 55 (5) 12 (22) 19 (35) 24 (44)  
 Other 14 (1) 5 (36) 6 (43) 3 (21)  
Cigarette pack-year      <.001
 None 423 (42)    423 (100)  
 1 - 30 339 (32) 86 (36) 253 (69)   
 >30 265 (26) 153 (64) 112 (31)   
Primary site      <.001
 Tonsil 460 (44) 111 (46) 171 (45) 178 (42)  
 Base of tongue 511 (49) 95 (39) 186 (49) 230 (54)  
 Other* 75 (7) 36 (15) 24 (6) 15 (4)  
T-category      <.001
 1-2 640 (62) 107 (44) 235 (62) 298 (71)  
 3-4 406 (38) 135 (56) 146 (38) 125 (30)  
N-category      .07
 0 57 (5) 20 (8) 22 (6) 15 (4)  
 1 -2a 317 (30) 63 (26) 120 (31) 134 (32)  
 2b – 2c 573 (55) 128 (53) 205 (54) 240 (57)  
 3 99 (9) 31 (13) 34 (9) 34 (8)  
Stage      .001
 3 206 (20) 43 (18) 83 (22) 80 (19)  
 4A 707 (68) 149 (62) 257 (68) 30 (72)  
 4B 133 (13) 50 (21) 41 (11) 42 (10)  
Treatment      .176
 XRT alone 415 (40) 83 (34) 158 (42) 175 (41)  
 CTXRT 389 (37) 102 (43) 146 (38) 141 (33)  
 Ind. CTX > XRT 118 (11) 29 (12) 35 (9) 53 (13)  
 Ind. CTX > CTXRT 124 (12) 28 (12) 42 (11) 54 (14)  
Radiation technique      <.001
 IMRT 714 (69) 141 (58) 211 (69) 316 (75)  
 3D conformal 328 (31) 101 (42) 120 (31) 107 (25)  
Radiation Fractionation      .442
 Once- daily 700 (67) 154 (64) 250 (66) 296 (70)  
 Altered fractionation 346 (33) 88 (36) 131 (34) 127 (30)  
  1. *Other primary sites: soft palate, 19 patients; pharyngeal wall, 34, NOS (not otherwise specified), 22.
  2. XRT – Radiotherapy; CTXRT – concurrent chemoradiation; Ind. CTX – Induction chemotherapy.