All (N= 1046) No. (%) | Current smokers (N= 242) No. (%) | Former smokers (N= 381) No. (%) | Never smokers (N= 423) No. (%) | p- value | |
---|---|---|---|---|---|
Age in years | |||||
Mean (range) | 56.2 (28–87) | 55.6 (35 – 80) | 59.3 (36 – 87) | 53.7 (28 – 81) | .01 |
Median | 55 | 55 | 58 | 53 | |
Sex | .725 | ||||
Male | 906 (87) | 207 (86) | 334 (88) | 365 (86) | |
Female | 140 (13) | 35 (14) | 47 (12) | 58 (14) | |
Race | <.001 | ||||
White | 930 (89) | 197 (21) | 353 (38) | 380 (41) | |
Black | 47 (5) | 29 (62) | 3 (6) | 15 (32) | |
Hispanic | 55 (5) | 12 (22) | 19 (35) | 24 (44) | |
Other | 14 (1) | 5 (36) | 6 (43) | 3 (21) | |
Cigarette pack-year | <.001 | ||||
None | 423 (42) | 423 (100) | |||
1 - 30 | 339 (32) | 86 (36) | 253 (69) | ||
>30 | 265 (26) | 153 (64) | 112 (31) | ||
Primary site | <.001 | ||||
Tonsil | 460 (44) | 111 (46) | 171 (45) | 178 (42) | |
Base of tongue | 511 (49) | 95 (39) | 186 (49) | 230 (54) | |
Other* | 75 (7) | 36 (15) | 24 (6) | 15 (4) | |
T-category | <.001 | ||||
1-2 | 640 (62) | 107 (44) | 235 (62) | 298 (71) | |
3-4 | 406 (38) | 135 (56) | 146 (38) | 125 (30) | |
N-category | .07 | ||||
0 | 57 (5) | 20 (8) | 22 (6) | 15 (4) | |
1 -2a | 317 (30) | 63 (26) | 120 (31) | 134 (32) | |
2b – 2c | 573 (55) | 128 (53) | 205 (54) | 240 (57) | |
3 | 99 (9) | 31 (13) | 34 (9) | 34 (8) | |
Stage | .001 | ||||
3 | 206 (20) | 43 (18) | 83 (22) | 80 (19) | |
4A | 707 (68) | 149 (62) | 257 (68) | 30 (72) | |
4B | 133 (13) | 50 (21) | 41 (11) | 42 (10) | |
Treatment | .176 | ||||
XRT alone | 415 (40) | 83 (34) | 158 (42) | 175 (41) | |
CTXRT | 389 (37) | 102 (43) | 146 (38) | 141 (33) | |
Ind. CTX > XRT | 118 (11) | 29 (12) | 35 (9) | 53 (13) | |
Ind. CTX > CTXRT | 124 (12) | 28 (12) | 42 (11) | 54 (14) | |
Radiation technique | <.001 | ||||
IMRT | 714 (69) | 141 (58) | 211 (69) | 316 (75) | |
3D conformal | 328 (31) | 101 (42) | 120 (31) | 107 (25) | |
Radiation Fractionation | .442 | ||||
Once- daily | 700 (67) | 154 (64) | 250 (66) | 296 (70) | |
Altered fractionation | 346 (33) | 88 (36) | 131 (34) | 127 (30) |