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Table 3 Relevant plan parameters of IMRT versus 3DCRT of 31 patients with upper abdominal tumors

From: Intensity modulated radiotherapy of upper abdominal malignancies: dosimetric comparison with 3D conformal radiotherapy and acute toxicity

 

IMRT

3DCRT

Difference

p-value†

Parameter

Mean

SD

Mean

SD

Mean

−95CI

+95CI

Timing of RT

Plan

Plan*Timing of RT

PTV

          

  HI

0.97

0.03

0.96

0.04

−0.01

−0.027

0.003

0.46

0.10

0.40

  CI

0.71

0.20

0.65

0.23

−0.06

−0.109

−0.005

0.17

0.03

0.22

Combined kidneys

         

  Mean dose (cGy)

1428

640

1322

656

−106

−256

44

0.01

0.16

0.46

  Maximum Dose (cGy)

3946

1418

4272

1130

325

58

593

0.06

0.02

0.23

  V12

59.7

31.9

41.3

23.03

−18.4

−28.6

−8.3

0.13

<0.01

0.75

  V20

26.8

19.4

22.3

17.7

−4.5

−8.63

−0.41

0.11

0.04

0.89

  V28

10.8

12.395

13.9

14.0

3.1

0.4

5.9

0.15

0.03

0.41

Liver

          

  Mean dose (cGy)

1593

817

1427

890

−165

−261

−69

0.39

<0.01

0.34

  Maximum Dose (cGy)

4924

945

4592

1377

−332

−723

58

0.76

0.10

0.67

Small bowel

          

  Mean dose (cGy)

4394

1686

4237

1800

−157

−556

242

0.27

0.39

0.15

  V15

62.2

22.5

54.9

20.9

−7.3

−1.0

−4.6

0.67

<0.01

0.19

Spinal cord

          

  Maximum Dose (cGy)

2940

1003

2999

1208

59

−269

386

0.83

0.72

0.89

  1. IMRT = Reversed planned intensity modulated radiotherapy; 3DCRT = Three-dimensional planned conformal radiotherapy; CI = 95% confidence interval: Timing of RT = Definitive radiotherapy versus postoperative radiotherapy; † = ANOVA with repeated measurements; Vx = Percentage of tissue volume encompassed by the x cGy isodose line; Plan = IMRT versus 3DCRT; Plan*Timing of RT = Interaction between plan and timing of RT.