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Table 1 Comparison of manometric data between before and after nCRT in 30 patients

From: Short–term effects of neoadjuvant chemoradiation therapy on anorectal function in rectal cancer patients: a pilot study

 

Before nCRT (N = 30)

After nCRT (N = 30)

P-value

MRP (mmHg)

93.5 ± 44.7

80.3 ± 32.4

0.195

R asymmetry (%)

22.3 ± 12.9

23.9 ± 9.7

0.572

MSP (mmHg)

348.8 ± 177.2

285.2 ± 111.7

0.102

S asymmetry (%)

17.2 ± 11.6

16.3 ± 4.8

0.667

HPZ length at rest (cm)

1.8 ± 0.6

1.8 ± 0.8

0.789

HPZ length at squeezing (cm)

2.2 ± 0.5

2.3 ± 0.8

0.634

RAIR (ml)

37.3 ± 13.6

40.7 ± 9.8

0.281

Rectal sensory threshold (ml)

 

First

63.0 ± 32.1

57.3 ± 18.9

0.408

Desire to defecate

117.3 ± 46.5

108.7 ± 42.3

0.453

Maximal

179.3 ± 63.7

151.7 ± 53.4

0.073

Rectal compliance (ml/mmHg)

1.4 ± 0.8

1.3 ± 0.7

0.638

  1. MRP Mean Resting Pressure, R asymmetry asymmetry of the resting sphincter, MSP Maximal Squeezing Pressure, S asymmetry asymmetry of the squeezing sphincter, HPZ High Pressure Zone, RAIR Recto-Anal Inhibitory Reflex, nCRT neoadjuvant chemoradiation therapy.