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Table 2 Survival analysis of all factors assessed by fDM

From: Identification of early and distinct glioblastoma response patterns treated by boron neutron capture therapy not predicted by standard radiographic assessment using functional diffusion map

  

All factors assessed by fDM

  

VD(%)

VI(%)

VNC(%)

Min ADC (10-5mm2/sec)

Max ADC (10-5mm2/sec)

RECIST (cm)

Volume reduction rate of enhanced lesion (%)

  

> 12.4

≤ 12.4

< 3.6

≥ 3.6

< 74.6

≥ 74.6

< 70

≥ 70

< 368

≥ 368

< 40.3

≥ 40.3

< −21.1

≥ −21.1

Median time (M)

19.3

10.3

11.2

12.1

15.3

11

14.3

9.1

11.2

12.1

14.2

10.8

15.1

9.7

95% CI

13.4-

7.8-

7.2-

7.8-

6.9-

7.8-

7.8-

7.2-

7.2-

6.9-

7.8-

7.2-

11.2-

7.2-

(M)

45.9**

13.4**

45.9

15.3

45.9

15.1

22.7**

10.8**

23.2

15.1

45.9

15.1

45.9

15.3

p value

log-rank

0.022*

0.521

0.128

0.011*

0.176

0.118

0.143

wilcoxon

0.033*

0.834

0.35

0.045*

0.413

0.223

0.083

  1. *VD and Min ADC at 2 days after BNCT showed a significant difference using log-rank test and wilcoxon test. **However, Min ADC showed over-lap in 95% CI. On the other hand, VD showed no over-lap in 95% CI.