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Table 2 Survival analysis of all factors assessed by fDM

From: Identification of early and distinct glioblastoma response patterns treated by boron neutron capture therapy not predicted by standard radiographic assessment using functional diffusion map

   All factors assessed by fDM
   VD(%) VI(%) VNC(%) Min ADC (10-5mm2/sec) Max ADC (10-5mm2/sec) RECIST (cm) Volume reduction rate of enhanced lesion (%)
   > 12.4 ≤ 12.4 < 3.6 ≥ 3.6 < 74.6 ≥ 74.6 < 70 ≥ 70 < 368 ≥ 368 < 40.3 ≥ 40.3 < −21.1 ≥ −21.1
Median time (M) 19.3 10.3 11.2 12.1 15.3 11 14.3 9.1 11.2 12.1 14.2 10.8 15.1 9.7
95% CI 13.4- 7.8- 7.2- 7.8- 6.9- 7.8- 7.8- 7.2- 7.2- 6.9- 7.8- 7.2- 11.2- 7.2-
(M) 45.9** 13.4** 45.9 15.3 45.9 15.1 22.7** 10.8** 23.2 15.1 45.9 15.1 45.9 15.3
p value log-rank 0.022* 0.521 0.128 0.011* 0.176 0.118 0.143
wilcoxon 0.033* 0.834 0.35 0.045* 0.413 0.223 0.083
  1. *VD and Min ADC at 2 days after BNCT showed a significant difference using log-rank test and wilcoxon test. **However, Min ADC showed over-lap in 95% CI. On the other hand, VD showed no over-lap in 95% CI.