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Table 1 Baseline clinical characteristics of the study group

From: Variations of circulating endothelial progenitor cells and transforming growth factor-beta-1 (TGF-β1) during thoracic radiotherapy are predictive for radiation pneumonitis

Characteristics

Number of patients

Percentage (%)

Number of patients

80

100

Age (years)

  

  Mean

58.5

 

  Range

38-70

 

Gender

  

  Male

48

60.0

  Female

32

40.0

KPS

  

  90-100

63

78.7

  80

17

21.3

AJCC clinical stage

  

  IIIA

35

43.8

  IIIB

45

56.2

Histology

  

  Adenocarcinoma

31

38.8

  Squamous cell

43

53.8

  Large cell carcinoma

3

3.7

  Other

3

3.7

Tumor site (lobe)

  

  Upper & middle

57

71.2

  Lower

23

28.8

Comorbidity

  

  COPD

7

8.8

  Cardiovascular disease

3

3.7

  Diabetes

3

3.7

Smoking history

  

  Nonsmoker

34

42.5

  Current or ex smoker

46

57.5

Chemotherapy

  

  Yes

56

70

  No

24

30

V20

  

  Mean

32.11

 

  Range

8.6-63.3

 

V30

  

  Mean

29.5

 

  Range

6.6-48.5

 

Weight loss ≥ 5%

  

  Yes

29

36.2

  No

51

63.8

  1. Abbreviations: COPD: chronic obstructive pulmonary disease, KPS: Karnofsky performance status.