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Table 5 Late toxicity (>90 days post CRT) by HPV status

From: Oropharyngeal squamous cell carcinoma with known human papillomavirus status treated with definitive chemoradiotherapy: patterns of failure and toxicity outcomes

Late toxicity

HPV-positive (86)

HPV-negative (17)

p-value

Need for feeding tube 6 months post-RT

0 (0%)

4 (24%)

<0.001

Normal diet at last follow up

77 (90%)

11 (65%)

0.017

Xerostomia grade ≥ 2

69 (80%)

13 (77%)

0.76

Dysphagia grade ≥ 2

14 (16%)

5 (29%)

0.20

Trismus grade ≥ 2

1 (1%)

4 (24%)

0.002