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Table 1 Incidence of TLN in subgroups defined by ROC curve analysis of rVX, aVX, Dmax and Dmean

From: Analysis of dosimetric factors associated with temporal lobe necrosis (TLN) in patients with nasopharyngeal carcinoma (NPC) after intensity modulated radiotherapy

Variable Range (median) Group No. of TLs Incidence of TLN χ 2 P value
rV10 6.8%–100%(37.86%) ≤42% 316 1.9% 53.360 0.000
>42% 185 22.2%
aV10 7.32–107.86 cc(29.00 cc) ≤38 cc 358 2.8%   
   >38 cc 143 25.9% 64.033 0.000
rV20 4.16%–100%(21.12%) ≤21% 272 0.7% 52.326 0.000
>21% 229 19.7%
aV20 2.93–107.86 cc(16.02 cc) ≤17 cc 294 0.7% 63.368 0.000
>17 cc 207 21.7%
rV30 1.80%–99.99%(12.67%) ≤20% 364 2.7%   
   >20% 137 27% 68.911 0.000
aV30 1.10–107.85 cc(9.39 cc) ≤15 cc 358 2.2%   
   >15 cc 143 27.3% 75.354 0.000
rV40 0.06%–99.52%(6.59%) ≤11% 363 2.5%   
   >11% 138 27.5% 73.846 0.000
aV40 0.04–107.34 cc(4.92 cc) ≤11 cc 409 2.7%   
   >11 cc 92 39.1% 117.321 0.000
rV50 0.00%–98.07%(2.49%) ≤5% 363 1.7%   
   >5% 138 29.7% 92.589 0.000
aV50 0.00–105.78 cc(1.92 cc) ≤4 cc 364 1.6%   
   >4 cc 137 29.9% 93.632 0.000
rV60 0.00%–92.58%(0.25%) ≤2% 422 4.0%   
   >2% 79 38.0% 90.200 0.000
aV60 0.00–99.86 cc(0.20 cc) ≤2 cc 430 4.0%   
   >2 cc 71 42.3% 105.150 0.000
rV66 0.00%–77.40%(0.00%) ≤0.1% 340 0.9%   
   >0.1% 161 27.3% 89.895 0.000
aV66 0.00–83.48 cc(0.00 cc) ≤0.2 cc 361 1.1%   
   >0.2 cc 139 30.2% 101.788 0.000
rV70 0.00%–50.65%(0.00%) ≤0.01% 351 1.7%   
   >0.01% 150 27.3% 81.166 0.000
aV70 0.00–54.64 cc(0.00 cc) ≤0.07 cc 380 2.4%   
   >0.07 cc 121 31.4% 91.021 0.000
Dmax 32.4–84.9 Gy(66.15 Gy) ≤68.85 Gy 321 0.6% 80.616 0.000
>68.85 Gy 180 25.0%
Dmean 3.9–35.7 Gy(11.70 Gy) ≤11.55 Gy 273 0.4% 57.347 0.000
   >11.55 Gy 228 20.2%