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Table 9 Summary of differences between treatment plan and radiobiological parameters from the two algorithms for prostate treatment

From: Clinical implications in the use of the PBC algorithm versus the AAA by comparison of different NTCP models/parameters

 

Parameters

 

AAA Mean

sd

PBC Mean

sd

p

PTV

D2%(Gy)

 

77.6

1.6

78.7

1.6

<0.001

 

D95%(Gy)

 

75.3

1.6

76.2

1.5

<0.001

 

Dmean(Gy)

 

76.5

1.5

77.4

1.6

<0.001

 

II(%)

 

3.2

0.1

3.2

0.2

0.416

 

TCP(%)α/β 1.49

 

81.9

5.1

83.9

4.3

<0.001

 

TCP(%)α/β 10.0

 

93.8

6.5

95.7

5.0

<0.001

Rectum

D2%(Gy)

 

74.3

1.6

77.0

2.0

<0.001

 

D50%(Gy)

 

41.7

6.5

40.7

6.8

<0.001

 

D95%(Gy)

 

21.1

4.8

18.6

4.7

<0.001

 

Dmean(Gy)

 

44.6

6.2

43.9

6.6

0.002

  

LKB model

     
 

NTCP (%)

Ref.

     
  

Rancati et al. [62]

3.3

1.9

3.9

2.5

0.005

  

Rancati et al. [62]

0.5

0.6

1.5

2.0

0.006

  

Tucker et al. [45]

9.2

2.2

11.5

2.3

<0.001

  

Peeters et al. [63]

3.1

1.9

4.1

2.9

<0.001

  

Söhn et al. [47]

4.5

1.8

6.4

2.6

<0.001

  

Rancati et al. [46]

9.1

2.2

11.1

2.2

<0.001

  

Seriality model

     
  

Rancati et al. [62]

3.0

1.8

3.5

2.4

0.013

Femoral heads

D2%(Gy)

 

55.2

3.6

54.5

3.8

0.104

 

D50%(Gy)

 

44.6

6.9

43.6

7.3

<0.001

 

D80%(Gy)

 

26.1

5.7

25.1

6.0

<0.001

  

LKB model

     
 

NTCP(%)

Ref.

     
  

Emami et al. [39] / Burman et al. [23]

0.2

0.1

0.1

0.1

<0.001

  1. Insignificant differences (p > 0.05) are in bold.