Table 8 Summary of differences between treatment plan and radiobiological parameters from the two algorithms for head-and-neck treatment

PTV

D_2%(Gy)

64.4

4.6

66.3

4.9

<0.001

D_95%(Gy)

60.2

4.6

62.5

5.0

<0.001

D_mean(Gy)

62.1

4.5

64.3

4.9

<0.001

II(%)

7.0

0.3

6.0

0.4

<0.001

TCP(%)

84.4

5.1

88.4

2.5

<0.001

parotid glands

D_mean(Gy)^*

35.7

1.8

36.6

1.7

<0.001

D_mean(Gy)^**

34.0

4.7

34.9

4.3

0.02

D_mean(Gy)

35.0

4.0

36.2

3.9

<0.001

LKB model

NTCP (%)

Ref.

Emami et al. [39] / Burman et al. [23]

12.8

3.0

15.2

2.7

0.002

Roesink et al. [42]

33.5

2.6

36.0

2.1

<0.001

Eisbruch et al. [41]

57.5

4.0

63.8

3.8

<0.001