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Table 5 Comparison of the literatures for radiotherapy in hepatocellular carcinoma patients with portal vein tumor thrombosis

From: Hypofractionated radiotheapy using helical tomotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis

Reference N Techniques Fraction size (Gy) Total dose (Gy) Response (%) Median survival (months)
Toya [10] 38 3D-CRT 1.8–4 40 (range, 17.5–50.4) CR = 15.8 9.6
      PR = 28.9  
Kim [11] 59 3D-CRT 2–3 30–54 CR = 6.8 Responder: 10.7
      PR = 39.0 Non-responder: 5.3
McIntosh [14] 20 Helical Tomotherapy 2.5 50 PR = 6.2 9.6
      SD = 87.5  
Choi [15] 9 Cyberknife 10–12 30–36 CR = 11.1 8
      PR = 33.3  
Current study 35 Helical Tomotherapy 4.5–6 50 (range, 45–60) CR = 14.3 12.9
      PR = 28.6 Responder 13.9
       Non-responder 6.9
  1. Abbreviations: Gy, Gray; PVTT, Portal vein tumor thrombosis; 3D-CRT, 3 dimensional conformal radiotherapy; CR, Complete response; PR, partial response; SD, Stable disease.