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Table 5 Comparison of the literatures for radiotherapy in hepatocellular carcinoma patients with portal vein tumor thrombosis

From: Hypofractionated radiotheapy using helical tomotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis

Reference

N

Techniques

Fraction size (Gy)

Total dose (Gy)

Response (%)

Median survival (months)

Toya [10]

38

3D-CRT

1.8–4

40 (range, 17.5–50.4)

CR = 15.8

9.6

     

PR = 28.9

 

Kim [11]

59

3D-CRT

2–3

30–54

CR = 6.8

Responder: 10.7

     

PR = 39.0

Non-responder: 5.3

McIntosh [14]

20

Helical Tomotherapy

2.5

50

PR = 6.2

9.6

     

SD = 87.5

 

Choi [15]

9

Cyberknife

10–12

30–36

CR = 11.1

8

     

PR = 33.3

 

Current study

35

Helical Tomotherapy

4.5–6

50 (range, 45–60)

CR = 14.3

12.9

     

PR = 28.6

Responder 13.9

      

Non-responder 6.9

  1. Abbreviations: Gy, Gray; PVTT, Portal vein tumor thrombosis; 3D-CRT, 3 dimensional conformal radiotherapy; CR, Complete response; PR, partial response; SD, Stable disease.