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Table 2 Postoperative survival of patients in relation to clinicopathological characteristics and microRNA expression analyzed by the Cox proportional hazard regression model in 60 cases

From: Overexpression of miRNA-21 promotes radiation-resistance of non-small cell lung cancer

Variables

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI) p

Hazard ratio (95% CI) p

Smoking

+/-

1.014(0.385-2.668) 0.978

1.351(0.477-3.831) 0.571

Age

≥60

1.111(0.528-2.338) 0.456

1.053(0.478-2.324) 0.897

Sex

M/F

1.265(0.481-3.331) 0.634

1.710(0.595-4.915) 0.319

LN metastasis

+/-

2.389(1.099-5.196) 0.025

2.045(1.072-3.513) 0.015

TNM

I+II/III

1.794(1.131-2.845) 0.003

4.021(1.764-6.462) 0.004

Differentitation

Well+mod/poor

1.283(0.656-2.508) 0.654

1.687(0.734-3.879) 0.218

miRNA-21

Low/High

2.827(1.274-6.275) 0.011

2.103(0.695-3.078) 0.032

  1. LN Lymph node, TNM Stage of Tumor, Regional Lymph node and Metastasis; CI Confidence Interval.