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Table 2 Postoperative survival of patients in relation to clinicopathological characteristics and microRNA expression analyzed by the Cox proportional hazard regression model in 60 cases

From: Overexpression of miRNA-21 promotes radiation-resistance of non-small cell lung cancer

Variables Univariate analysis Multivariate analysis
Hazard ratio (95% CI) p Hazard ratio (95% CI) p
Smoking +/- 1.014(0.385-2.668) 0.978 1.351(0.477-3.831) 0.571
Age ≥60 1.111(0.528-2.338) 0.456 1.053(0.478-2.324) 0.897
Sex M/F 1.265(0.481-3.331) 0.634 1.710(0.595-4.915) 0.319
LN metastasis +/- 2.389(1.099-5.196) 0.025 2.045(1.072-3.513) 0.015
TNM I+II/III 1.794(1.131-2.845) 0.003 4.021(1.764-6.462) 0.004
Differentitation Well+mod/poor 1.283(0.656-2.508) 0.654 1.687(0.734-3.879) 0.218
miRNA-21 Low/High 2.827(1.274-6.275) 0.011 2.103(0.695-3.078) 0.032
  1. LN Lymph node, TNM Stage of Tumor, Regional Lymph node and Metastasis; CI Confidence Interval.