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Table 1 Patient, tumor and previous RT characteristics

From: Hypofractionated radiosurgery for intact or resected brain metastases: defining the optimal dose and fractionation

n = 42 patients

n (%)Median (range)

Age

58 years (23-81)

Gender

 

 Male

19 (45%)

 Female

23 (55%)

Performance Status

 

 ECOG 0-2

37 (88%)

 ECOG 3-4

5 (12%)

Primary Cancer Diagnosis

 

 Breast

12 (29%)

 Lung, NSCLC

10 (24%)

 Melanoma

9 (21%)

 Head and Neck

5 (12%)

 Other/Unknown

6 (14%)

Intact Brain Metastasis

20 (48%)

Resection Cavity

22 (52%)

 GTR

11

 STR

11

Target Volume

 

 GTV/Cavity Maximum Dimension

3.9 cm (0.8-6.4 cm)

 GTV/Cavity Volume

13.6 cc (0.2 – 57.0 cc)

 PTV Volume

24.5 cc (0.8 – 122.0 cc)

Previous RT and Dose to HR site

 

 None

20 (48%)

 WBRT

5 (12%)

 

37.5 Gy (30-45)

 SRS

5 (12%)

 

18 Gy (5-21)

 IMRT

4 (10%)

 

47.5 Gy (10-60)

 Combination

8 (19%)

 

41.25 Gy (10 -75)

Time from Previous RT to HR

13 months (0.3-32.4)

  1. Abbreviation: NSCLC, non-small cell lung cancer.